Scenario D. Cystic fibrosis is à genetic descent. It is caused by a rare recessive allele at a gene that exhibits complete dominance (N = norm= allele, C = disease allele). You sample 1000 European descendants in a U.S. population and find 772 NN individuals, 221 NC heterozygotes, and 7 CC individuals with cystic fibrosis. %3D
Scenario D. Cystic fibrosis is à genetic descent. It is caused by a rare recessive allele at a gene that exhibits complete dominance (N = norm= allele, C = disease allele). You sample 1000 European descendants in a U.S. population and find 772 NN individuals, 221 NC heterozygotes, and 7 CC individuals with cystic fibrosis. %3D
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Scenario D. Cystic fibrosis is a genetic disease in humans that mostly affects people of European
descent. It is caused by a rare recessive allele at a gene that exhibits complete dominance (N = normal
allele, C = disease allele). You sample 1000 European descendants in a U.S. population and find 772
NN individuals, 221 NC heterozygotes, and 7 CC individuals with cystic fibrosis.
You might find the following equations useful for the questions below:
p +q = 1
p2 + 2pq + q² = 1
x? = 2 (0-E/IE
x cutoff = 3.84
SHOW YOUR WORK!
18. What is the frequency of the Nallele?
19. What is the expected frequency of the CC genotype under Hardy-Weinberg equilibrium?
20. Calculate the x?-statistic to determine whether the population is in Hardy-Weinberg equilibrium.
21. The data ( rejects / fails to reject ) the null hypothesis, and the data ( accepts / rejects )
Hardy-Weinberg equilibrium for this particular gene. Explain how you decided,
creenshot (1).png
Show A
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