Answered: Sarcomere A-band H-zone Thin filament…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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A few hours after the death of an animal, the corpse will stiffen as a result of continued contraction of muscle tissue (this state is called rigor mortis). This phenomenon is the result of the loss of ATP production in muscle tissue.
(a) Consult as shown and describe, in terms of the six-step model of muscle contraction, how a lack of ATP in sarcomeres would result in rigor mortis.
(b) The Ca²⁺ transporter in sarcomeres that keeps the [Ca²⁺]∼10^-7 M
requires ATP to drive transport of Ca²⁺ ions across the membrane of the
sarcoplasmic reticulum. How would a loss of this Ca²⁺ transport function
result in the initiation of rigor mortis?
(c) Rigor mortis is maximal at ∼12 hrs after death and by 72 hrs is no
longer observed. Propose an explanation for the disappearance of rigor
mortis after 12 hrs.

Sarcomere
A-band
H-zone
Thin filament (actin)
Thlck fillament (myosin)
Z-llne
-band
ATP binds to myosin head.
Actin-binding slte on myosin
releases from actin.
ADP Is
released.
ADP
АТР
Actin-blnding site
dloses followed by
Muscle contractlon
H,0-
power stroke as
myosin head
retracts.
ATP hydrolysls.
Myosin head "cocks."
API
P,release results
In strong blnding of
myosin head to actin.
Weak binding of
myosin head to actin.
A FIGURE 7.48 A model of the ATP cycle in muscle contraction. For clarity, only one of the two myosin
headpieces is shown going through a binding, power stroke, and release cycle. The second myosin head-
piece is shown in light green. The individual steps of the cycle are described in the text.

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