Ran and Rab are both involved in transport of proteins in the cell. Match the function with the correct protein. Involved in nuclear import/export A. Ran GEF When bound to GTP, binds import receptor, and B. Ran GAP releases cargo into nucleus C. Rab • Plays a role in targeting vesicles to correct membrane D. Ran When GTP is hydrolyzed releases vesicle and effector
Ran and Rab are both involved in transport of proteins in the cell. Match the function with the correct protein. Involved in nuclear import/export A. Ran GEF When bound to GTP, binds import receptor, and B. Ran GAP releases cargo into nucleus C. Rab • Plays a role in targeting vesicles to correct membrane D. Ran When GTP is hydrolyzed releases vesicle and effector
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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
Transcribed Image Text:**Transcription and Explanation for Educational Use**
**Topic: Role of Ran and Rab Proteins in Cellular Transport**
**Interactive Activity: Matching Functions with Proteins**
Ran and Rab are both involved in the transport of proteins within the cell. The following activity allows you to match each function with the correct protein.
**Match the function with the correct protein:**
1. **Involved in nuclear import/export**
- A. Ran GEF
- B. Ran GAP
- C. Rab
- D. Ran
2. **When bound to GTP, binds import receptor, and releases cargo into nucleus**
- A. Ran GEF
- B. Ran GAP
- C. Rab
- D. Ran
3. **Plays a role in targeting vesicles to correct membrane**
- A. Ran GEF
- B. Ran GAP
- C. Rab
- D. Ran
4. **When GTP is hydrolyzed releases vesicle and effector**
- A. Ran GEF
- B. Ran GAP
- C. Rab
- D. Ran
**Diagram Explanation:**
This activity highlights the specific roles played by Ran and Rab proteins in cellular mechanisms. The interactive element challenges the learner to correctly associate the functional roles with the respective proteins, emphasizing key concepts in cellular transport and protein regulation.
**Note**: Ran GEF (guanine nucleotide exchange factors) and Ran GAP (GTPase-activating proteins) are involved in regulating Ran's activity. Rab proteins are key for vesicle transport specificity.
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