Question 9 has been shown to be an efficient support for the asymmetric 1,2-Trans-cyclohexanediol cyclopropanation of allylic ethers as shown in the scheme below. Et₂Zn + CICH₂l Toluene 3 h, -20°C OH OH Bu NI TI₂O CH₂Cl₂ and=a PhLi THF -100°C (a) Draw the structure of the zinc reagent formed from EtzZn and CICHal that allows for the ultimate formation of the cyclopropene ring. (b) The zinc reagent gives the 'active' organic molecule that completes the ring formation. Draw the structure of this 'active' molecule. (c) What name is given to each of your answers to parts (a) and (b). The complex in part (a) can be described as a... The molecule in part (b) can be described as a... Page 17 of 18
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Need help with part b). Thank you :)
Step by step
Solved in 3 steps with 3 images