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Question 8 Which of the following IS a Phase Il metabolic reaction? O Fornation of a ketone at a benzylic carbon O Formation of a sulfate from an alcohol O Formation of a carboxrylic acid and alcohol from an ester O Formation of a carboxylic acid from a primary methyl group Question 9 A drug has a hepatic extraction ratio (EH) of 0.3 and is 70% absorbed from the gut. The bioavailability is: O 0.10 O 0.40 O 0.49 O 021

Question 8 Which of the following IS a Phase Il metabolic reaction? O Fornation of a ketone at a benzylic carbon O Formation of a sulfate from an alcohol O Formation of a carboxrylic acid and alcohol from an ester O Formation of a carboxylic acid from a primary methyl group Question 9 A drug has a hepatic extraction ratio (EH) of 0.3 and is 70% absorbed from the gut. The bioavailability is: O 0.10 O 0.40 O 0.49 O 021

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question 8 Which of the following IS a Phase II metabolic reaction? O Formation of a ketone at a benzylic carbon O Formation of a sulfate from an alcohol O Formation of a carboxylic acid and alcohol from an ester O Formation of a carboxylic acid from a primary methyl group Question 9 A drug has a hepatic extraction ratio (EH) of 0.3 and is 70% absorbed from the gut. The bioavailability is: O 0.10 O 0.40 O 0.49 O 0.21
Transcribed Image Text:Question 8 Which of the following IS a Phase II metabolic reaction? O Formation of a ketone at a benzylic carbon O Formation of a sulfate from an alcohol O Formation of a carboxylic acid and alcohol from an ester O Formation of a carboxylic acid from a primary methyl group Question 9 A drug has a hepatic extraction ratio (EH) of 0.3 and is 70% absorbed from the gut. The bioavailability is: O 0.10 O 0.40 O 0.49 O 0.21
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