QUESTION 25 A college student, Matt, comes to the Emergency Department has a very low blood pressure (64/49), rapid heart and respiratory rates, and a fever. Despite many drugs and intravenous infusions, it is impossible to get his blood pressure up and eventually Matt has multi-organ failure and dies. Blood cultures grow Neisseria meningitidis. What is the best description of Matt's illness? O Group A Strep sequelae O meningococcal sepsis O Ventilator-Associated Pneumonia QUESTION 26 Matt from the previous question had had his spleen removed many years ago. The spleen is a major antibody-producing organ. Why was Matt exceptionally susceptible to a bloodstream infection by Neisseria meningitidis? O The spleen normally traps and holds N. meningitidis until cytotoxic T cells can kill it. O There is actually no connection between the lack of a spleen and susceptibility to blood-borne infections. ON. meningitidis has an anti-phagocytic capsule. Matt did not have opsonizing antibodies to help phagocytes attach to the pathogen. Click Save and Submit to save and submit. Click Save All Answers to save all answers. Save A e Type here to search (? 29°F

Human Anatomy & Physiology (11th Edition)
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### Educational Case Study: Understanding Neisseria Meningitidis Infection 

#### Question 25

**Case Study:** A college student, Matt, comes to the Emergency Department with very low blood pressure (64/49), rapid heart and respiratory rates, and a fever. Despite many drugs and intravenous infusions, it is impossible to stabilize his blood pressure, and eventually, Matt experiences multi-organ failure and dies. Blood cultures reveal the presence of *Neisseria meningitidis*.

**Question:** What is the best description of Matt's illness?
- Group A Strep sequelae
- Meningococcal sepsis
- Ventilator-Associated Pneumonia

#### Question 26

Matt from the previous question had his spleen removed many years ago. The spleen is a major antibody-producing organ. **Question:** Why was Matt exceptionally susceptible to a bloodstream infection by *Neisseria meningitidis*?

- The spleen normally traps and holds *N. meningitidis* until cytotoxic T cells can kill it.
- There is actually no connection between the lack of a spleen and susceptibility to blood-borne infections.
- *N. meningitidis* has an anti-phagocytic capsule. Matt did not have opsonizing antibodies to help phagocytes attach to the pathogen.

#### Instructions
Click “Save and Submit” to record your responses. Click “Save All Answers” to save all your answers without submitting.

---

This case study explores the serious implications of a *Neisseria meningitidis* infection and illustrates the critical role the spleen plays in fighting such infections.
Transcribed Image Text:### Educational Case Study: Understanding Neisseria Meningitidis Infection #### Question 25 **Case Study:** A college student, Matt, comes to the Emergency Department with very low blood pressure (64/49), rapid heart and respiratory rates, and a fever. Despite many drugs and intravenous infusions, it is impossible to stabilize his blood pressure, and eventually, Matt experiences multi-organ failure and dies. Blood cultures reveal the presence of *Neisseria meningitidis*. **Question:** What is the best description of Matt's illness? - Group A Strep sequelae - Meningococcal sepsis - Ventilator-Associated Pneumonia #### Question 26 Matt from the previous question had his spleen removed many years ago. The spleen is a major antibody-producing organ. **Question:** Why was Matt exceptionally susceptible to a bloodstream infection by *Neisseria meningitidis*? - The spleen normally traps and holds *N. meningitidis* until cytotoxic T cells can kill it. - There is actually no connection between the lack of a spleen and susceptibility to blood-borne infections. - *N. meningitidis* has an anti-phagocytic capsule. Matt did not have opsonizing antibodies to help phagocytes attach to the pathogen. #### Instructions Click “Save and Submit” to record your responses. Click “Save All Answers” to save all your answers without submitting. --- This case study explores the serious implications of a *Neisseria meningitidis* infection and illustrates the critical role the spleen plays in fighting such infections.
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