QUESTION 2 Consider the following reaction. What is the role of LDA? CHOUyEt 1.LDA, THF 2.CH₂CH₂Br O LDA acts as an acid to protonate the carbonyl carbon to form a good electrophile. LDA acts as a base and removes a proton from the alpha carbon to form the enolate. OLDA acts as a nucleophile and is substituted by the THF. OLDA acts as an electrophile and adds to the alkyl halide so it is easier to substitute. CH₂CH₂ CHCO₂Et

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QUESTION 2
Consider the following reaction. What is the role of LDA?
CH,COyEt
1.LDA, THF
2.CH₂CH₂Br
OLDA acts as an acid to protonate the carbonyl carbon to form a good electrophile.
LDA acts as a base and removes a proton from the alpha carbon to form the enolate.
OLDA acts as a nucleophile and is substituted by the THF.
OLDA acts as an electrophile and adds to the alkyl halide so it is easier to substitute.
CH₂CH₂
CHCO₂Et
Transcribed Image Text:QUESTION 2 Consider the following reaction. What is the role of LDA? CH,COyEt 1.LDA, THF 2.CH₂CH₂Br OLDA acts as an acid to protonate the carbonyl carbon to form a good electrophile. LDA acts as a base and removes a proton from the alpha carbon to form the enolate. OLDA acts as a nucleophile and is substituted by the THF. OLDA acts as an electrophile and adds to the alkyl halide so it is easier to substitute. CH₂CH₂ CHCO₂Et
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