Question 13Propose a meaning for v/VmO The velocity as a fraction of the maximal velocityO The parabolic rate function of the inverse maximal rateO The minimal reaction rateO The difference between the actual rate and the maximal rateQuestion 5Two enzymes have Enzyme Commission classifications as E.C.2.1.3.9 and E.C.1.1.3.9.How are the enzymes different?O They act on different acceptorsO They catalyze different reactionsO They bind different cofactorsO They act on different donor groups D.Question 14Consider the Lineweaver-Burk plots of two enzyme activities on the left. How isenzyme A different from enzyme B?1/vB1/[S]O Enzyme A has a negative KmO Enzyme A requires more substrate to achieve the same rateO Enzyme A has a smaller Km/Vm ratioEnzvme A is slower

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Answered: Question 13 Propose a meaning for v/Vm…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter20: Electron Transport And Oxidative Phosphorylation

Section: Chapter Questions

Problem 19P

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In an enzymatic reaction: a. the enzyme leaves the reaction chemically unchanged. b. if the enzyme molecules approach maximal rate, and the substrate is continually increased, the rate of the reaction does not reach saturation. c. in the stomach, enzymes would have an optimal activity at a neutral pH. d. increasing temperature above the optimal value slows the reaction rate. e. the least important level of organization for an enzyme is its tertiary structure.
Understanding Human Energy Consumption During Exercise Energy production in animals is related to oxygen consumption. The ruby-throated hummingbird consumes about 250 mL of oxygen per hour during its migration across the Gulf of Mexico. Use this number and the data in problem 11 to determine a conversion factor for energy expended per liter of oxygen consumed. If a human being consumes 12.7 kcal/min while running 8-minute miles, how long could a human run on the energy that the hummingbird consumes in its trans-Gulf flight? How many 8-minute miles would a person have to run to lose 1 pound of body fat?
Which of the following analogies best describes the induced-fit model of enzyme-substrate binding? a hug between two people a key fitting into a lock a square peg fitting through the square bole and a round peg fitting through the round hole of a children’s toy the fitting together of two jigsaw puzzle pieces
In the following graph: A represents the product. B represents the energy of activation when enzymes are present. C is the free energy difference between A and D. C is the energy of activation without enzymes. E is the difference in free energy between the reactant and the products.
Which of the following statements about inhibition is true? a. Allosteric inhibitors and allosteric activators are competitive for a given enzyme. b. If an inhibitor binds the active site, it is considered noncompetitive. c. If an inhibitor binds to a site other than the active site, this competitive inhibition. d. A noncompetitive inhibitor is believed to change the shape of the enzyme, making its active site inoperable. e. Competitive inhibition is usually not reversible.
Which of the following methods is not used by enzymes to increase the rate of reactions? a. covalent bonding with the substrate at their active site b. bringing reacting molecules into close prosimity c. orienting reactants into positions to favor transition states d. changing charges on reactants to hasten their reactivity e. increasing fit of enzyme and substrate that reduces the energy of activation
Which of the following comparisons or contrasts between endergonic and exergonic reactions is false? Endergonic reactions have a positive ?G and exergonic reactions have a negative ?G Endergonic reactions consume energy and exergonic reactions release energy Both endergonic and exergonic reactions require a small amount of energy to overcome an activation barrier Endergonic reactions take place slowly and exergonic reactions take place quickly.
Which of the following statements about the allosteric site is true? a. The allosteric site is a second active site on a substrate in a metabolic pathway. b. The allosteric site on an enzyme can allow the product of a metabolic pathway to inhibit that enzyme and stop the pathway. c. When the allosteric site of an enzyme is occupied, the reaction is irreversible and the enzyme cannot react again. d. An allosteric activator prevents binding at the active site. e. An enzyme that possesses allosteric sites does not possess an active site.
Test Your Understanding 8. Induced fit means that when a substrate binds to an enzymes active site, (a) it fits perfectly, like a key in a lock (b) the substrate and enzyme undergo conformational changes (c) a site other than the active site undergoes a conformational change (d) the substrate and the enzyme become irreversibly bound to each other (e) c and d
Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy charge. a. Would hexokinase be an R enzyme or a U enzyme? Would glutamine: PRPP amidotransferase, the second enzyme in purine biosynthesis, be an R enzyme or a U enzyme? b. If energy charge = 0.5: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low? c. If energy charge = 0.95: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low?
PREDICT In the following reaction series, which enzyme(s) is/are most likely to have an allosteric site to which the end product E binds? (a) enzyme 1 (b) enzyme 2 (c) enzyme 3 (d) enzyme 4 (e) enzymes 3 and 4
When two glucose molecules react to form maltose: a. the reaction represents a negative G. b. free energy had to be available to allow the reaction to proceed. c. the reaction is exothermic. d. it supports the second law of thermodynamics, which states there is tendency of the universe toward disorder. e. the resulting product has less potential energy than the reactants.

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Question 13 Propose a meaning for v/Vm O The velocity as a fraction of the maximal velocity O The parabolic rate function of the inverse maximal rate O The minimal reaction rate O The difference between the actual rate and the maximal rate