Q37: A patient arrives in the emergency room apparently in cardiogenic shock due to a massive heart attack. His initial arterial blood sample reveals the following concentrations of ions: Sodium Bicarbonate Free calcium Potassium pH 137 mmol/L 14 mmol/L 2.8 mmol/L 4.8 mmol/L 7.16 To correct the acidosis, the attending physician begins an infusion of sodium bicarbonate and after 1 hr takes another blood sample, which reveals the following values: Sodium Bicarbonate Free calcium Potassium pH 138 mmol/L 22 mmol/L 2.3 mmol/L 4.5 mmol/L 7.34

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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Q37: A patient arrives in the emergency room apparently in cardiogenic shock due to a massive heart
attack. His initial arterial blood sample reveals the following concentrations of ions:
Sodium
Bicarbonate
Free calcium
Potassium
pH
To correct the acidosis, the attending physician begins an infusion of sodium bicarbonate and after 1 hr
takes another blood sample, which reveals the following values:
Sodium
Bicarbonate
Free calcium
Potassium
pH
137 mmol/L
14 mmol/L
2.8 mmol/L
4.8 mmol/L
7.16
138 mmol/L
22 mmol/L
2.3 mmol/L
4.5 mmol/L
7.34
What is the cause of the decrease in calcium ion concentration?
A. The increase in arterial pH resulting from the sodium bicarbonate infusion inhibited parathyroid
hormone secretion
B. The increase in pH resulted in the stimulation of osteoblasts, which removed calcium from the
circulation
C. The increase in pH resulted in an elevation in the concentration of HPO42, which shifted the
equilibrium between HPO42 and Ca11 toward CaHPO4
Answer: C
D. The increase in arterial pH stimulated the formation of 1,25-dihydroxycholecalciferol, which resulted
in an increased rate of absorption of calcium from the gastrointestinal tract
Transcribed Image Text:Q37: A patient arrives in the emergency room apparently in cardiogenic shock due to a massive heart attack. His initial arterial blood sample reveals the following concentrations of ions: Sodium Bicarbonate Free calcium Potassium pH To correct the acidosis, the attending physician begins an infusion of sodium bicarbonate and after 1 hr takes another blood sample, which reveals the following values: Sodium Bicarbonate Free calcium Potassium pH 137 mmol/L 14 mmol/L 2.8 mmol/L 4.8 mmol/L 7.16 138 mmol/L 22 mmol/L 2.3 mmol/L 4.5 mmol/L 7.34 What is the cause of the decrease in calcium ion concentration? A. The increase in arterial pH resulting from the sodium bicarbonate infusion inhibited parathyroid hormone secretion B. The increase in pH resulted in the stimulation of osteoblasts, which removed calcium from the circulation C. The increase in pH resulted in an elevation in the concentration of HPO42, which shifted the equilibrium between HPO42 and Ca11 toward CaHPO4 Answer: C D. The increase in arterial pH stimulated the formation of 1,25-dihydroxycholecalciferol, which resulted in an increased rate of absorption of calcium from the gastrointestinal tract
Expert Solution
Introduction

A disturbance in the body's acid-base balance characterises metabolic acidosis, a dangerous electrolyte disease. Increased acid production, bicarbonate loss, and a diminished ability of the kidneys to eliminate extra acids are the three main underlying causes of metabolic acidosis. Acidemia, which is defined as arterial blood pH less than 7.35, can result from metabolic acidosis. [7] Since acidemia and acidosis do not necessarily coexist, pH levels in people with metabolic acidosis can range from low to high. Hydrogen ion concentrations also depend on the coexistence of other acid-base disorders.

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