Q1- Given the following information for a drug which follows linear one compartment pharmacokinetics, calculate Cp at 0.5, 1, 2, 4, 6, 12 hours after a 200 mg i.v. bolus dose. Use kel = 0.12 hr; V = 145 L. Present the data in a table form (with all applicable units) and plot C, vs. t and InC, vs. t. Label the graphs and axes appropriately. Dose Cp = xe-keit V %3D

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Q1- Given the following information for a drug which follows linear one compartment
pharmacokinetics, calculate Cp at 0.5, 1, 2, 4, 6, 12 hours after a 200 mg i.v. bolus dose. Use kel =
0.12 hr'; V = 145 L. Present the data in a table form (with all applicable units) and plot C, vs. t
and InCp vs. t. Label the graphs and axes appropriately.
Dose
Cp =
xe-keit
V
Transcribed Image Text:Q1- Given the following information for a drug which follows linear one compartment pharmacokinetics, calculate Cp at 0.5, 1, 2, 4, 6, 12 hours after a 200 mg i.v. bolus dose. Use kel = 0.12 hr'; V = 145 L. Present the data in a table form (with all applicable units) and plot C, vs. t and InCp vs. t. Label the graphs and axes appropriately. Dose Cp = xe-keit V
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