Purpose: To determine the effectiveness of Cognitive Remediation (CR) programs on cognition, symptoms and functioning of those experiencing a first episode of psychosis. Studies eligible for inclusion in the review: Studies were included if they (1) were an RCT, (2) all, or a distinct subgroup of participants were experiencing a first episode psychosis, and (3) the intervention met the definition of Cognitive Remediation. CR is defined as a behavioural training-based intervention that aims to improve cognitive processes such as attention, memory, executive function, social cognition and metacognition The primary outcome in the systematic review was global symptoms. The meta- analysis for the systematic review is found in the table below. Figure 1. Forest plot of the effect of CR on global symptoms Std. Mean Difference SE Weight V. Random, 95% Cl 0.22 -0.17, 0.61] -0.49 -1.16, 0.18] 0.48 -0.07, 1.031 0.17 -0.24, 0.58] 0.18 -0.53, 0.891 0.49 F0.29, 1.271 0.07 -0.69, 0.831 0.54 (0.05, 1.031 -0.01 F0.60, 0.58) 0.25 -0.51, 1.01) -0.37 -1.21, 0.471 Std. Mean Difference Std. Mean Difference V, Random, 95% CI Study or Subgroup Christensen et al (2014) Drake et al (2013) Eack et al (2009) Fisher et al (2014) Hotzer et al (2014) Lee et al (2013) Mendella et al (2015) Ojeda et al (2011) Puig et al (2014) Ueland & Rund (2004) wykes et al (2007) 0.22 -0.49 0.34 0.48 0.28 0.2 19.4% 6.7% 0.17 0.21 0.18 0.36 0.49 9.9% 17.6% 6.0% 4.9% 0.4 0.07 0.39 0.54 0.25 12.4% 5.1% -0.01 0.3 8.6% 0.25 0.39 5.1% 4.2% -0.37 0.43 Total (95% CI) 100.0% 0.19 [0.02, 0.36] Heterogeneity. Tau = 0.00; Chi² = 9.89, df = 10 (P = 0.45), P= 0% Test for overall effect Z = 2.14 (P= 0.03) Favours control Favours CR Was the primary outcome analyzed as a continuous or dichotomous outcome? Explain your answer.
Purpose: To determine the effectiveness of Cognitive Remediation (CR) programs on cognition, symptoms and functioning of those experiencing a first episode of psychosis. Studies eligible for inclusion in the review: Studies were included if they (1) were an RCT, (2) all, or a distinct subgroup of participants were experiencing a first episode psychosis, and (3) the intervention met the definition of Cognitive Remediation. CR is defined as a behavioural training-based intervention that aims to improve cognitive processes such as attention, memory, executive function, social cognition and metacognition The primary outcome in the systematic review was global symptoms. The meta- analysis for the systematic review is found in the table below. Figure 1. Forest plot of the effect of CR on global symptoms Std. Mean Difference SE Weight V. Random, 95% Cl 0.22 -0.17, 0.61] -0.49 -1.16, 0.18] 0.48 -0.07, 1.031 0.17 -0.24, 0.58] 0.18 -0.53, 0.891 0.49 F0.29, 1.271 0.07 -0.69, 0.831 0.54 (0.05, 1.031 -0.01 F0.60, 0.58) 0.25 -0.51, 1.01) -0.37 -1.21, 0.471 Std. Mean Difference Std. Mean Difference V, Random, 95% CI Study or Subgroup Christensen et al (2014) Drake et al (2013) Eack et al (2009) Fisher et al (2014) Hotzer et al (2014) Lee et al (2013) Mendella et al (2015) Ojeda et al (2011) Puig et al (2014) Ueland & Rund (2004) wykes et al (2007) 0.22 -0.49 0.34 0.48 0.28 0.2 19.4% 6.7% 0.17 0.21 0.18 0.36 0.49 9.9% 17.6% 6.0% 4.9% 0.4 0.07 0.39 0.54 0.25 12.4% 5.1% -0.01 0.3 8.6% 0.25 0.39 5.1% 4.2% -0.37 0.43 Total (95% CI) 100.0% 0.19 [0.02, 0.36] Heterogeneity. Tau = 0.00; Chi² = 9.89, df = 10 (P = 0.45), P= 0% Test for overall effect Z = 2.14 (P= 0.03) Favours control Favours CR Was the primary outcome analyzed as a continuous or dichotomous outcome? Explain your answer.
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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