Provide the major product(s) from the following reaction.

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Provide the major product(s) from the following reaction.

The image shows a chemical reaction involving a cyclohexane derivative. The starting material is a bicyclic structure with an alcohol group (OH) on a cyclohexane ring. Two hydrogen atoms (H) are shown with solid and dashed wedges, indicating the stereochemistry at specific positions.

The reaction proceeds in two steps:

1. **TsCl, pyridine**: The first step involves treating the compound with p-toluenesulfonyl chloride (TsCl) and pyridine. This transforms the alcohol group into a tosylate, a better leaving group, facilitating substitution reactions.

2. **NaN₃, DMF**: In the second step, sodium azide (NaN₃) is used in the presence of dimethylformamide (DMF) as a solvent. This step leads to the substitution of the tosylate group with an azide group (N₃), resulting in an azido cyclohexane derivative.

This reaction sequence is a typical method for converting alcohols to azides, which can further participate in various chemical transformations.
Transcribed Image Text:The image shows a chemical reaction involving a cyclohexane derivative. The starting material is a bicyclic structure with an alcohol group (OH) on a cyclohexane ring. Two hydrogen atoms (H) are shown with solid and dashed wedges, indicating the stereochemistry at specific positions. The reaction proceeds in two steps: 1. **TsCl, pyridine**: The first step involves treating the compound with p-toluenesulfonyl chloride (TsCl) and pyridine. This transforms the alcohol group into a tosylate, a better leaving group, facilitating substitution reactions. 2. **NaN₃, DMF**: In the second step, sodium azide (NaN₃) is used in the presence of dimethylformamide (DMF) as a solvent. This step leads to the substitution of the tosylate group with an azide group (N₃), resulting in an azido cyclohexane derivative. This reaction sequence is a typical method for converting alcohols to azides, which can further participate in various chemical transformations.
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