Proteins are composed of long chains of amino acids linked together through amide bonds. In the body, protease enzymes break down proteins into the individual amino acids by hydrolyzing the amide bonds. Propose a plausible curved arrow mechanism for the hydrolysis of the dipeptide shown below into the amino acids glycine and alanine under acidic conditions. H,0 HO. H* H2N он dipeptide glycine alanine

Introduction to General, Organic and Biochemistry
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ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter22: Proteins
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Proteins are composed of long chains of amino acids linked together through amide bonds. In
the body, protease enzymes break down proteins into the individual amino acids by hydrolyzing the amide
bonds. Propose a plausible curved arrow mechanism for the hydrolysis of the dipeptide shown below
into the amino acids glycine and alanine under acidic conditions.
H20
H+
HO
H2N.
H2N
H2N
+
HO,
dipeptide
glycine
alanine
Transcribed Image Text:Proteins are composed of long chains of amino acids linked together through amide bonds. In the body, protease enzymes break down proteins into the individual amino acids by hydrolyzing the amide bonds. Propose a plausible curved arrow mechanism for the hydrolysis of the dipeptide shown below into the amino acids glycine and alanine under acidic conditions. H20 H+ HO H2N. H2N H2N + HO, dipeptide glycine alanine
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