Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter17: Aldehydes And Ketones
Section: Chapter Questions
Problem 17.61P
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Question
Propose two syntheses of 4-phenyl-2-pentanone, each involving conjugate addition of a lithium diorganocopper reagent.
Expert Solution
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Step 1
The product given is 4-phenyl-2-pentanone.
Gilman reagent is an organo copper lithium reagent which is used to form a carbon-carbon bond.
The two way by which 4-phenyl-2-pentanone can be formed using the help of Gilman reagent is shown below:
First method:
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