Propose an efficient synthesis for the following transformation: The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A В C H2O, H2SO4, HØSO4 t-BUOK HBr, ROOR F HC=CNa Br2, hv HBr H 1) R2BH 1) O3 2) H2O H2, Pd 2) H2O2, H2O
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
The transformation above can be performed with some reagent or combination of the reagents listed below. Provide the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as “EBF”). If there is more than one correct solution, provide just one answer.
**Reagents:**
- **A**: H₂O, H₂SO₄, HgSO₄
- **B**: t-BuOK
- **C**: HBr, ROOR
- **D**: HC≡CNa
- **E**: Br₂, hv
- **F**: HBr
- **G**: H₂, Pd
- **H**:
1) O₃
2) H₂O
- **I**:
1) R₂BH
2) H₂O₂, H₂O
**Note:** Use the reagent letters to propose a synthesis pathway for the given transformation.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc40367ef-9d16-46b4-a881-300c62159ba4%2Ffcd87903-c24d-4e66-8e21-2ba632ff134c%2Fo27ax_processed.png&w=3840&q=75)
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
