BACKGROUND: Sickle cell disease is caused by a change in the gene for hemoglobin, which isthe oxygen-carrying protein in red blood cells. Individuals who are homozygous for the sicklecell trait often cannot endure exercise. Individuals who are heterozygous for the trait can havesickle cell attacks under extreme conditions. Normal individuals (genotype: Hbnorm Hbnorm ) haveonly normal hemoglobin. Homozygous sickle cell individuals (genotype: Hbsc Hbsc ) 'have onlysickle cell hemoglobin. Heterozygous individuals (genotype: Hbnorm Hbsc ) have both normal andsickle cell hemoglobin.terry Smith collapsed while running a race for his track team. A doctor said he had a sickle cellattack. Genetic tests were run on several family members. The test results are shown below. AnX indicates that form of hemoglobin in red blood cells.PROBLEM: How can you determine the genotypes of people in a family?SubjectNormal HemoglobinSickle Cell HemoglobinJerryJerry's brotherJerry's younger sisterJerry's youngest sisterJerry's fatherJerry's grandfatherJerry's grandmotherPROCEDURE1. Use the background information and the genetic test results to answer questions 1-4.2. Use the background information and a Punnett square to help you answer question 5.ANALYZE AND CONCLUDE1. Are any of Jerry's siblings homozygous for the sickle cell trait? Are any of Jerry's siblingsheterozygous for the sickle cell trait?2. What genotype if Jerry's father?3. What genotypes are Jerry's grandparents?4. What is the genotype of Jerry's mother? Explain.5. If Jerry marries a female who is heterozygous for the sickle cell trait, what would be thepossible genotypes and phenotypes of their childres, according to your Punnett square?

Hbn Hbn =homozygous normalHbs Hbs = homozygous recessive with diseaseHbn Hbs= heterozygous normal

PROCEDURE 1. Use the background information and the genetic test results to answer questions 1-4. 2. Use the background information and a Punnett square to help you answer question 5. ANALYZE AND CONCLUDE 1. Are any of Jerry's siblings homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for the sickle cell trait? 2. What genotype if Jerry's father? 3. What genotypes are Jerry's grandparents? 4. What is the genotype of Jerry's mother? Explain. 5. If Jerry marries a female who is heterozygous for the sickle cell trait, what would be the possible genotypes and phenotypes of their childres, according to your Punnett square?

PROCEDURE 1. Use the background information and the genetic test results to answer questions 1-4. 2. Use the background information and a Punnett square to help you answer question 5. ANALYZE AND CONCLUDE 1. Are any of Jerry's siblings homozygous for the sickle cell trait? Are any of Jerry's siblings heterozygous for the sickle cell trait? 2. What genotype if Jerry's father? 3. What genotypes are Jerry's grandparents? 4. What is the genotype of Jerry's mother? Explain. 5. If Jerry marries a female who is heterozygous for the sickle cell trait, what would be the possible genotypes and phenotypes of their childres, according to your Punnett square?

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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can you help with question 1 plz. thank you!
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O. exal B. Heredity Assume that dominant allele is B (brown eye color) and that recessive allele is b (blue eye color). Genotype of the father (male) is BB. Genotype of the mother (female) is Bb, Questions: 7. List all the possible genotypes and phenotypes and calculate the probability of each. 8. What is the probability of this couple having a child with brown eyes? What about blue eyes? Add Tip omment ASK Question Dow 5,288 66 APR 28 étv 260
Concerning aneuploidy questions. YES/NO a. Is the age of the mother a significant factor? b. Does aneuploidy occur more frequently in a particular ethnic group? c. Does the mother’s behavior during the pregnancy (smoking, drinking, poor nutrition, drug abuse) contribute to aneuploidy? d. If a couple has a child with a particular chromosomal disorder, are they more likely than other couples of having a second child with the same disorder?