Problem 3: https://doi.org/10.1021/ja9093988 Answer to Problem 3: Hint. Assume the reaction can ONLY occur from the least sterically hindered side of the molecule. Draw or build a 3-dimentional conformation to support your answer. H CO₂Me H2 ? PtO2 HO A B с D H CO₂Me H CO₂Me H CO₂Me H CO₂Me HO HO HO

please include a readable explanation

Select the lowest-energy conformation of the compound shown at the top. i Oi =: E: iii O iv V iv

For the substituted cyclohexane compound shown, identify the atoms that will interact with the methyl group in a 1,3-diaxial fashion after rotation to the other chair conformation. BF Br E C HI A CI H3C- HK CIH These atoms will interact with methyl in a 1,3-diaxial interaction. B A E K HOJ FD H HE HG