Pro- inflammatory chemicals Blood clot Bacteria entering via wound Inflammatory mediators are released response to microbial components and tissue damage. Phagocytic cells destroy and remove invaders. -Neutrophil Resident macrophage Blood vessel Neutrophil -Recruited macrophage 20 Monocyte Leaky capillary Neutrophils are the first phagocytes recruited to the site. Normal blood flow in the tissues As the infection is brought under as the injury occurs. control, macrophages ingest dead cells and debris. (a) Tighter Diapedesis Loose adherence; adherence cells tumble to a halt. Inflammatory mediators cause small blood vessels to dilate. The phagocytic cells tumble to a halt and then squeeze between the endothelial cells and enter the tissues. (Ь) FIGURE 14.15 The Inflammatory Response (a) The process of inflammation. (b) Phagocytes leave the blood vessels and move to the site of infection.

Q: What factors control the plasma protein systems of inflammation?

A: The inflammatory reaction occurs in a variety of situations accompanied by quite dramatic changes in…

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Q: List the sequence of events in an inflammatory response and describe each step.

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Q: How do T cells reach the CNS of healthy individuals?

A: Question -  How do T cells reach the CNS of healthy individuals?

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Q: Discuss the events in the inflammatory response ?

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Q: An experimental animal is given a drug that blocks phagocytosis. Will this drug prevent the animal’s…

A: The immune system is the system that provides protection against the foreign bodies or disease…

Q: What do Target tissues for cytokines includes?

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Q: Identify the cells that initiate inflammation and thecells that are activated by inflammatory…

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Q: What is the role of Role of NK Cells?

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Q: What Release histamine, promote inflammation?

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Q: explain the concepts of inflammation

A:

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Q: What type of feedback is exemplified by the secretion of interferon-gamma by NK cells?

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Q: Name the sources of the major inflammatory mediators

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