Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
Problem 13E
Related questions
Question
![## Organic Chemistry Reaction Question
### Instructions
Modify the given structure of the starting material to draw the major product.
### Starting Material Structure
The figure shows a chemical structure with a benzene ring attached to a bromine (Br) atom via a two-carbon chain. The image is interactive, with an 'Edit Drawing' button below the structure.
<button style="background-color: #007bff; color: white; padding: 5px 10px; border: none; border-radius: 5px;">
Edit Drawing
</button>
Please use the provided drawing tool to modify the structure and predict the major product of the reaction, based on the given starting material.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5a114021-58c6-4a9b-be47-596443b986c0%2F225ae79b-0f6b-46ec-aad5-bc4f5a304f85%2F6leo5vy_processed.png&w=3840&q=75)
Transcribed Image Text:## Organic Chemistry Reaction Question
### Instructions
Modify the given structure of the starting material to draw the major product.
### Starting Material Structure
The figure shows a chemical structure with a benzene ring attached to a bromine (Br) atom via a two-carbon chain. The image is interactive, with an 'Edit Drawing' button below the structure.
<button style="background-color: #007bff; color: white; padding: 5px 10px; border: none; border-radius: 5px;">
Edit Drawing
</button>
Please use the provided drawing tool to modify the structure and predict the major product of the reaction, based on the given starting material.
![**Predict the major product(s) for the following reaction:**
**Reaction Scheme:**
1. The reactant is a bromobenzene.
2. The bromobenzene is treated with \(\ce{Mg}\) (Step 1).
3. The resulting Grignard reagent is then reacted with formaldehyde (Step 2).
4. The final step involves the addition of an acid workup (\(\ce{H3O+}\)) to the reaction mixture (Step 3).
**Diagrams and Symbols:**
- The benzene ring with a bromine atom (\(\ce{Br}\)) attached is shown as the starting material.
- In Step 1, the reagent \(\ce{Mg}\) is added, which indicates the formation of a Grignard reagent.
- In Step 2, an aldehyde (\(\ce{HCHO}\)) is introduced as the second reagent.
- Finally, the acidic workup with \(\ce{H3O+}\) (Step 3) follows.
The expected major product will be an alcohol, formed through the following process:
1. Formation of the Grignard reagent \(\ce{C6H5-MgBr}\).
2. Nucleophilic addition of the Grignard reagent to formaldehyde (\(\ce{HCHO}\)), forming \(\ce{C6H5-CH2O^-}\).
3. Protonation of the alkoxide ion with \(\ce{H3O+}\) to yield \(\ce{C6H5-CH2OH}\).
Note:
- The question is asking to predict the products of a multi-step organic reaction mechanism involving a Grignard reagent.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5a114021-58c6-4a9b-be47-596443b986c0%2F225ae79b-0f6b-46ec-aad5-bc4f5a304f85%2Fse1rq5c_processed.png&w=3840&q=75)
Transcribed Image Text:**Predict the major product(s) for the following reaction:**
**Reaction Scheme:**
1. The reactant is a bromobenzene.
2. The bromobenzene is treated with \(\ce{Mg}\) (Step 1).
3. The resulting Grignard reagent is then reacted with formaldehyde (Step 2).
4. The final step involves the addition of an acid workup (\(\ce{H3O+}\)) to the reaction mixture (Step 3).
**Diagrams and Symbols:**
- The benzene ring with a bromine atom (\(\ce{Br}\)) attached is shown as the starting material.
- In Step 1, the reagent \(\ce{Mg}\) is added, which indicates the formation of a Grignard reagent.
- In Step 2, an aldehyde (\(\ce{HCHO}\)) is introduced as the second reagent.
- Finally, the acidic workup with \(\ce{H3O+}\) (Step 3) follows.
The expected major product will be an alcohol, formed through the following process:
1. Formation of the Grignard reagent \(\ce{C6H5-MgBr}\).
2. Nucleophilic addition of the Grignard reagent to formaldehyde (\(\ce{HCHO}\)), forming \(\ce{C6H5-CH2O^-}\).
3. Protonation of the alkoxide ion with \(\ce{H3O+}\) to yield \(\ce{C6H5-CH2OH}\).
Note:
- The question is asking to predict the products of a multi-step organic reaction mechanism involving a Grignard reagent.
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