**Title:** Predicting Major Products in Organic Reactions**Question:** Predict the major product(s) for each of the following reactions:**Reaction Scheme:**1. **Starting Compound:** A cyclic ester (lactone) structure comprised of a six-membered ring with two oxygen atoms; one in the ring and one as a carbonyl group.2. **Reagents:** - Step 1: Phenylmagnesium Bromide (PhMgBr) - Step 2: Aqueous Acid (H₃O⁺)**Expected Products:**- The reaction involves a nucleophilic addition of phenylmagnesium bromide (a Grignard reagent) to the carbonyl group of the lactone. Following the addition, hydrolysis with aqueous acid leads to a ring opening and the formation of an alcohol. - The product shown is a compound featuring: - A phenyl group attached to what was previously the carbonyl carbon. - An open chain with a hydroxyl (OH) group indicating alcohol formation.This transformation is typical of Grignard additions to esters and lactones, yielding tertiary alcohols via nucleophilic acyl substitution followed by hydrolysis.

Answered: Image /qna-images/answer/bee0543a-6ec1-4365-b4d7-760b0fcb88ec.jpg

Answered: Predict the major product(s) for each…

Science

Chemistry

Predict the major product(s) for each of the following: [3 1) PhMgBr 2) H₂O* ?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: Which of the following are a major product of the reaction sequence shown below? (1) Br2, FeBry (2)…

A: Organic chemistry.

Q: Predict the products of the following ether cleavage reactions: (a) (b) CH3 (c) CH₂CH3 HI H₂O…

A: All the given reactions are examples of acid catalysed cleavage of ether to give alcohols.

Q: Which are the major products of the reaction shown below? Na CH;CH3 "Br CH3CH2OH (A) (B) (C) (D) O…

A: It is an example of E2 elimination reaction to give alkene.

Q: 1) Predict the major product for the reaction shown. (CH3)2CHCH₂Cl AICI 3 ODE

A: Alkyl halide in presence of Lewis acid give electrophilic aromatic substitution reaction on benzene…

Q: What reagent is needed to complete the following reaction? B None of these A U CH3 CH3I (A) ??? IN 3…

A: Here nucleophilic substitution occurred, I- is the leaving group , so N3- is the nucleophile. Hence…

Q: Which of these gives mostly the meta product when treated with Br2 / * ?Fe a. b. HN d. O-CH,

A: The question is based on the concept of organic reactions. We have to identify the product formed…

Q: Which of the following is the major product of the reaction shown below? NOCH,CH, CH;CH,OH (A) (B)…

Q: any carbonyl (e) compound of 5 carbons or less (1) OEt H H -0

A: In this question, we will synthesized the products from the starting materials by using the…

Q: Predict the MAJOR product for the following reaction: 1) excess CH3l 2) Ag20, H20, heat (D) none of…

Q: Provide/ Draw the major product/s of the following reactions

Q: None

Q: What is the major organic product that occurs when (2R, 4S) 4- bromo-5-methyl-2-nitrohexane is…

A: The reaction involves the elimination of HBr to form an alkene derivative.

Q: Identify the structure of the product of the following reaction. 1) mCPBA 2) PhMgBr 3) H₂O*

A: In this question, we will find the product for this given incomplete reaction. Starting material is…

Q: Draw the starting structure that would lead to the major product shown under the provided…

A: An arrow always depicts from a region of high electron density to low electron density ; that is…

Q: Which compound is the dominant product in the reaction shown below? Br2 Br (A) (B) Br hv Br (C) (D)…

A: A photochemical reaction is a chemical reaction in which light energy is absorbed by a substance's…

Q: X) Predict the product for the reaction shown. SO3H H3O+ A I HO IV II پرد II (E III + V A) I B) II…

A: Thank you.

Q: Draw the MAJOR product(s) of the following reactions.

Q: (a) (b) + 1) LDA 2) Ć HH 3) H30* 1) NaOMe 2) H30*

A: NaOMe acts as a base .It will abstract acidic proton . LDA stands for Lithium diisopropyl amide .It…

Q: rrent Attempt in Progress Identify the major and minor product(s) of the following reaction: Br…

Q: i) Ph2PH ii) Nal iii) PhCH2OH iv) CH3SH v) Pr2CuLi At what letter in the picture will each above…

A: The reaction between substrate and reagent depends on the soft-hard acid base concept. A soft…

Q: Predict the structure of the product formed (with correct stereochemistry) for each of the following…

A: Gilman reagent is the organo copper reagent. Its formula is R2CuLi where is R is any alkyl or aryl…

Q: d) 1) CH,MgBr 2) H₂O*

A: Grignard reagents are identified as the compounds represented using the general formula of R-MgX.…

Q: b) KMN04 H20, OH-

A: Here we have to write the major product of the reaction-

Q: (а) -C- -ОН (b) -0-CH3 (c) -CI (d) C-CH3 (е) -NH3

A: Answer:- This question is answered by using the simple concept of effect of substituent on the…

Q: Vhich of the compounds below is the major product of the following reaction? (1) Hg(OAc)/ H,O/THF…

Q: "hich of the compounds below would be a major product of the following reaction? (1)…

A: NaBH4 is less reactive thus it can't reduce ester but it reduces ketones to their corresponding…

Q: Question 1 Predict the MAJOR organic product of the following reaction. 1) KMnO4, H₂O, heat 2) H3O+

A: Potassium permanganate is a strong oxidizing agent. Side chain oxidation of aryl alkanes takes place…

Q: Which of the following compounds will dominate the product distribution of the reaction shown? HC…

A: Given reaction is : 2,3-dimethyl-1,3-butadiene + HCl ----------> A + B + C + D What are the…

Q: Write the complete stepwise mechanism for the reaction below: (Non-anonymous question Ⓒ) OH HC1 OCH3…

Q: What is the major product of the following reaction? (A) (B) H2 Pd'Baso, (C) (D) O Compound B…

A: Lindlar catalyst: Alkynes can be selectively reduced to an alkene by reaction with hydrogen in…

Q: ill 11.5 Identify reagents that can be used to achieve each of the following transformations: 1) Na…

A: Information of question

Q: [ 19] What is major product of following sequence of reaction ? Hg(OAc)2 NABH4 AICI3 H20 Он он ОН Он…

A: The major product in the sequence of the reaction has to be found.

Q: Draw the product Y of the following reaction sequence. Y was anintermediate in the remarkable…

A: In the given reaction, the nucleophilic attack will takes place and followed by the elimination…

Q: Which of the following compounds is the dominant product of the reaction shown below? Br2 Br (B) Br…

A: Benzene undergo electrophilic aromatic substitution

Q: Which of the following are the major deuterated products of the reaction below? (1) Hg(OAc)2,…

A: Cyclo haxene compound is a reaction of Hg(oAc)2.H2O,THF/NaBD4,ethanol. What are following compounds…

Q: Draw the product for each of the following reactions: (a) NaN₁ H₂O ? (b) CH₂OH H₂SO4 ?

A: -> Epoxide ring can opened with nucleophile and form alcohol.-> In presence of acid…

Q: [7] What is major product of following sequence of reaction ? Hg(OAC)2 NABH4 ? AICI3 H20 OH OH ÓH ÓH…

Q: Identify the major product for the following reaction. (CH3)2CuLi H₂O H*

A: Organic compounds can be defined as the compounds that contain carbon and hydrogen atoms in a…

Q: None

A: Friedel-Crafts Alkylation is the introduction of an alkyl group to the benzene in presence of a…

Q: Please don't provide the handwriting solution whats the major product of the following?

A: Given are two reactions of pent-1,3-diene with:Br2 at 20oC. This is a conjugate addition reaction of…

Q: Give the products of the following reactions. A) B) C) D) Rxn l Rxn II Rxn ! A A CO₂Me Rxn II -CO₂Me…

A: Diene adds to dienophile to form corresponding addition product is known as Diels-Alder reaction.

Q: Provide the necessary reactants to make these following transformations/l 1) 2) 3) H3C H OH NH₂ H₂C…

A: These are aminoacid synthesis from acid, which requires reaction with ammonia at last step as shown…

Q: Which compound is the major product of the reaction below? H2 Pd'charcoal (A) (B) (C) (D) O Compound…

A: The above reaction is catalytic hydrogenation of alkene with hydrogen on the metal surface Pd/C.…

Q: Predict the major product(s) of the following reaction. HBr (1 equiv.) O Br OH OH Br Br ?

A: The objective of the question is to find the major product of the given reaction with reagent HBr.

Question

Expert Solution

Step 1

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Selection Rules for Pericyclic Reactions

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

13). What is the major product of the following two reactions? H₂ H3C H3C NH (A) H3C ОН H3C NH₂ OH-, then H2O (D) H3C H₂ (В) CH3 ? H3C H3C (E) ОН NH (C) CH3 -CH₂
12.60 Predict the major product of the following reaction. Mof O-S (a) (c) CN OUS=O 7 NaCN acetone (b) (d) ? CN
Major product?
[ 24] what is major product of following ? 'NH LIAIH4 NH2 `NH `NH `NH "ОН ОН (a) (b) (c) (d ) НО o (e)
Major product?
Give the major product(s) of the following reaction. 1) 03 2) Zn, H₂O ?
Identify the major product for the following reaction. NH, 1)excess CH3I 2) Ag20, H20, heat A D O A B C D
9) Which of the following is the major E2 product formed from the following alkyl halide? A) I G 11 CI III B) II IV C) III D) IV
00 Enter your answer in the provided box. After 0.600 L of Ar at 1.06 atm and 203°C is mixed with 0.200 L of O, at 399 torr and 120°C in a 400.-mL flask at 29°C, what is the pressure in the flask? atm 并 & $4 () 6) e k
What is the product of the followng reaction?
Identify the major organic product for the following reaction
What is the product of the following mixed Claisen reaction? (1) LDA -78 °C (2) add slowly (a) (b) HQ OH (c) (d) Answer (a) Answer (b) Answer (c) O Answer (d) O O O 0