Predict the major product(s) for each of the following: [3 1) PhMgBr 2) H₂O* ?

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**Title:** Predicting Major Products in Organic Reactions

**Question:** Predict the major product(s) for each of the following reactions:

**Reaction Scheme:**

1. **Starting Compound:** A cyclic ester (lactone) structure comprised of a six-membered ring with two oxygen atoms; one in the ring and one as a carbonyl group.

2. **Reagents:**
   - Step 1: Phenylmagnesium Bromide (PhMgBr)
   - Step 2: Aqueous Acid (H₃O⁺)

**Expected Products:**

- The reaction involves a nucleophilic addition of phenylmagnesium bromide (a Grignard reagent) to the carbonyl group of the lactone. Following the addition, hydrolysis with aqueous acid leads to a ring opening and the formation of an alcohol. 

- The product shown is a compound featuring:
  - A phenyl group attached to what was previously the carbonyl carbon.
  - An open chain with a hydroxyl (OH) group indicating alcohol formation.

This transformation is typical of Grignard additions to esters and lactones, yielding tertiary alcohols via nucleophilic acyl substitution followed by hydrolysis.
Transcribed Image Text:**Title:** Predicting Major Products in Organic Reactions **Question:** Predict the major product(s) for each of the following reactions: **Reaction Scheme:** 1. **Starting Compound:** A cyclic ester (lactone) structure comprised of a six-membered ring with two oxygen atoms; one in the ring and one as a carbonyl group. 2. **Reagents:** - Step 1: Phenylmagnesium Bromide (PhMgBr) - Step 2: Aqueous Acid (H₃O⁺) **Expected Products:** - The reaction involves a nucleophilic addition of phenylmagnesium bromide (a Grignard reagent) to the carbonyl group of the lactone. Following the addition, hydrolysis with aqueous acid leads to a ring opening and the formation of an alcohol. - The product shown is a compound featuring: - A phenyl group attached to what was previously the carbonyl carbon. - An open chain with a hydroxyl (OH) group indicating alcohol formation. This transformation is typical of Grignard additions to esters and lactones, yielding tertiary alcohols via nucleophilic acyl substitution followed by hydrolysis.
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