Predict Hb's affinity for oxygen at different conditions in the blood (in the lungs, in the tissues, pH changes, low & high oxygen levels, 2,3-BPG, fetal Hb)?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Predict Hb's affinity for oxygen at different conditions in the blood (in the lungs, in the tissues, pH changes, low & high oxygen levels, 2,3-BPG, fetal Hb)?

 

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Introduction

A protein present in the erythrocytes that transports oxygen from the lungs to the cells and tissues and transports carbon dioxide from cells and tissues to the lungs is referred to as hemoglobin. Each hemoglobin consists of 4 heme or iron groups to which the oxygen binds. So each hemoglobin can carry 4 oxygen molecules.

Factors that affect the affinity of hemoglobin for oxygen include:

  • Temperature
  • pH
  • 2,3-BPG
  • Carbon monoxide
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