Please with the information provided how do I draw a balanced equation for the reactions by using acetic anhydride as the acylating agent and dicholomethane as the reaction solvent.
Please with the information provided how do I draw a balanced equation for the reactions by using acetic anhydride as the acylating agent and dicholomethane as the reaction solvent.
Chapter17: Alcohols And Phenols
Section17.SE: Something Extra
Problem 77AP
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Please with the information provided how do I draw a balanced equation for the reactions by using acetic anhydride as the acylating agent and dicholomethane as the reaction solvent.

Transcribed Image Text:of the 7-bonds of benzene to
ring and regenerate the catalyst (step 3). When the acyl group is acetyl (CH3
as the acylating agent rather than acetyl chloride. The anhydride is safer to work with and it usually prov
better yields and a simpler work-up. More catalyst is needed with acetic anhydride however, because som
the aluminum chloride complexes with the acetic acid produced during the reaction, making it ineffective
catalyst. As a rule, 2-3 moles of AlCl3 are used per mole of acetic anhydride.
Step 1
Step 2
Step 3
R
H
+
CI
R
+
AICI 3
R
R
acylium ion
R
+
+ H+
AICI4
arenium ion
AICI4
Figure EAS.2: Mechanism of Friedel-Crafts acylation
R
AICI3 + HCI

Transcribed Image Text:Friedel-Crafts Acylation Reaction
Draw a balanced equation for the reaction. Include drawings of the structures of the reactant and all three
possible methoxyacetophenone isomers.
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