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Please indicate the coordination number and coordination geometry for the anticancer drug, cisplatin given in the picture

Please indicate the coordination number and coordination geometry for the anticancer drug, cisplatin given in the picture

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Please indicate the coordination number and coordination geometry for the anticancer drug, cisplatin given in the picture.

 

The image shows the chemical structure of cisplatin, an antineoplastic agent used in cancer treatment. The molecule is composed of a platinum (Pt) atom at the center with two ammonia (H₃N) ligands and two chloride (Cl) ligands. These groups are arranged in a square planar geometry, with the two ammonia molecules and the two chloride ions located adjacent to each other, forming a 'cis' configuration. In the diagram: - "H₃N" represents an ammonia molecule. - "Cl" represents a chloride ion. - "Pt" is the central platinum atom. This arrangement is crucial for the molecule’s biological activity, as it allows cisplatin to interact with DNA in cancer cells, thereby inhibiting their division and growth.
Transcribed Image Text:The image shows the chemical structure of cisplatin, an antineoplastic agent used in cancer treatment. The molecule is composed of a platinum (Pt) atom at the center with two ammonia (H₃N) ligands and two chloride (Cl) ligands. These groups are arranged in a square planar geometry, with the two ammonia molecules and the two chloride ions located adjacent to each other, forming a 'cis' configuration. In the diagram: - "H₃N" represents an ammonia molecule. - "Cl" represents a chloride ion. - "Pt" is the central platinum atom. This arrangement is crucial for the molecule’s biological activity, as it allows cisplatin to interact with DNA in cancer cells, thereby inhibiting their division and growth.
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