Please complete the reactions below. For b, add a substrate. For the other reactions, write down the major product (s). Hints: for e, hydride (from LIAIH4) serves as the nucleophile in the first step. a. H,SO̟ 180ºC b. 1) но. "Li 2) H¿O* LO Na+ CH,Br
Please complete the reactions below. For b, add a substrate. For the other reactions, write down the major product (s). Hints: for e, hydride (from LIAIH4) serves as the nucleophile in the first step. a. H,SO̟ 180ºC b. 1) но. "Li 2) H¿O* LO Na+ CH,Br
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:### Reaction Completion and Product Identification
Please complete the reactions below. For reaction "b," add a substrate. For the other reactions, write down the major product(s).
**Hints:** For "e," hydride from LiAlH₄ serves as the nucleophile in the first step.
#### Reaction Details
**a.**
- **Starting Material:** Cyclohexanol
- **Reagent/Conditions:** H₂SO₄, 180°C
- **Expected Reaction:** Dehydration to form cyclohexene.
**b.**
- **Starting Material:** Phenyl lithium
- **Reagents:**
1. Lithium reagent
2. H₃O⁺
- **Expected Process:** Nucleophilic addition followed by protonation.
**c.**
- **Starting Material:** Sodium phenoxide
- **Reagent:** CH₃Br
- **Expected Reaction:** Williamson ether synthesis to form anisole (methoxybenzene).
**d.**
- **Starting Material:** 3,3-Dimethyl-1-butanol
- **Reagent:** HBr
- **Expected Reaction:** Conversion to alkyl bromide through substitution.
**e.**
- **Starting Material:** Cyclopentanone
- **Reagents:**
1. LiAlH₄, (CH₃CH₂)₂O
2. H₃O⁺, H₂O
- **Expected Reaction:** Reduction to form cyclopentanol.
Note: The reactions detailed above are fundamental transformations often encountered in organic chemistry, with specific emphasis on mechanisms like dehydration, nucleophilic addition, Williamsons' ether synthesis, and reductions involving hydrides.
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