Peptide #1:  L-I-T-V Peptide #2:  C-Q-H-R Peptide #3:  E-G-E-A   Which peptide is the most basic?  Why?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Peptide #1:  L-I-T-V
Peptide #2:  C-Q-H-R
Peptide #3:  E-G-E-A

 

Which peptide is the most basic?  Why?

Expert Solution
Introduction

Amino acids are the building blocks of protein. An amino acid contains a carboxylic acid and a-amino group, hence called amino acids. Two amino acids are linked to one another by a peptide bond. There are 20 different types of amino acids. Amino acids can be classified as four depending upon their polarity:

  1. Non-polar, neutral: Sidechains that contains hydrocarbon alkyl group or aromatic group are usually non-polar.
  2. Polar and neutral: A neutral amino acid is an amino acid that doesn't have an overall charge in them.
  3. Acidic and polar: If the amino acid contains an acid group in its R chain, then it becomes an acidic amino acid.
  4. Basic and polar: If the R group contains an amine then the overall nature of the amino acid becomes basic.
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