People with two copies of the sickle cell gene are often quite ill with sickle cell anemia, while those with two copies of normal hemoglobin are likely tobecome quite ill with malaria where it occurs. Heterozygotes suffer few effects of sickle cell anemia, and are considerably resistant to malaria. In areaswhere malaria occurs, it exertson the human population.O A. Directional selectionO B. Disruptive selectionO C. Bimodal selectionO D.Stabilizing selectionO E. None of the above«< Question 20 of 120A Moving to another question will save this response.12:0112/16/26.PgUpPgDnF12PrtScnF8HomeF9EndF10F11DIIF5F7F6F4F3&#378.9.3YUR近

Name: People with two copies of the sickle cell gene are often quite ill wi
Uploaded: 2024-03-20T06:42:55.000Z
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Description: People with two copies of the sickle cell gene are often quite ill with sickle cell anemia, while those with two copies of normal hemoglobin are likely tobecome quite ill with malaria where it occurs. Heterozygotes suffer few effects of sickle cell

Sickle cell disease is a hereditary disease which affects the hemoglobin molecules.It was first discovered in 1904 .This disorder occurs because of change in single nucleotide in the gene which encodes for beta hemoglobin.Sickle cell mutation results in change of sixth amino acid in beta hemoglobin chain from glutamic acid to valine.Let's understand what is balancing selection; Balancing selection involves various processes through which active maintainence of multiple alleles in gene pool of a population occurs. One mechanism of balancing selection is when heterozygote have more fitness as compared to homozygotes.Hence genetic polymorphism is conserved. Example of balancing selection is sickle cell anemia . Sickle cell gene from one parent and a normal hemoglobin allele from other parent = heterozygote individual= normal life expectancy=carrier of sickle cell trait=resistant to malaria parasites=heterozygote advantage=balancing selectionSo correct option is D) D) Balancing selection