People with beriberi, a disease caused by thiamine deficiency, have elevated levels of blood pyruvate and oa-ketoglutarate, especially after consuming a meal rich in glucose. How are these effects related to a deficiency of thiamine?

Q: What type of reaction is catalyzed by  these complexes? Describe the role of dihydrolipoamide…

A: Dihydrolipoamide dehydrogenase (DLD) is present in pyruvate dehydrogenase complex which catalyzes…

Q: Deficiencies in the conversion of Pyruvate to Acetyl CoA may result in severe neurological…

A: Conversion of pyruvate to acetyl-CoA is the reaction that links glycolysis with the TCA…

Q: Ketone bodies that build up under starvation conditions act as hunger suppressants and mental…

A: Hi, Thanks For Your Question.  Answer : Our Bodies Get Energy From The Food We Eat. When We Are…

Q: Increased levels of NADH in the liver promote the process of gluconeogenesis. What do you make of…

A: Introduction: The process of synthesis of glucose or glycogen from non-carbohydrate sources in the…

Q: Can you explain the difference in the regulation of carbohydrate metabolism in liver and muscle?

A: A carbohydrate is a biological molecule containing atoms of oxygen, hydrogen, and carbon. The…

Q: If all of the pentose phosphate pathway is functioning (both oxidative and non-oxidative portions),…

A: Pentose Phosphate Pathway, also called the HMP shunt pathway is a multipurpose biochemical pathway…

Q: Why is oxaloacetate depletion from the TCA cycle important for the initiation of ketogenesis? What…

A: The TCA cycle is a central metabolic pathway that occurs in the mitochondria of cells and is…

Q: you follow a carbohydrate-free diet, certain metabolic problems occur. Describe glucogenesis and the…

A: Glucogenesis is the formation of glucose within an animal body from any product of glycolysis.…

Q: The antidiabetes drugs known as thiazolidinediones induce the production of glycerol kinase in…

A: Thiazolidinedione’s are a class of medicines that can be used in the treatment of type 2 diabetes.…

Q: Consider the fatty acids: (a) Arachidic acid (C20H40O2); molar mass = 312.5 g/mol) (b) Palmitoleic…

A: β-oxidation generally occurs in the mitochondria, and it is the pathway for degradation of fatty…

Q: What would be the effect on fatty acid synthesis of an increase in intramitochondrial oxaloacetate…

A: Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of…

Q: How does a ketogenic diet decrease the level of urea in obese patients and increase the level of…

A: Acetyl-coA, which is formed from the B-oxidation of fatty acids, is used to make ketones. Ketone…

Q: What would be the effect on fatty acid synthesis of an increase in intramito- chondrial oxaloacetate…

A: An increase in the level of oxaloacetate would cause the oxaloacetate to be converted to acetyl-CoA,…

Q: What impact would an increase in intramitochondrial oxaloacetate have on fatty acid synthesis?…

A: Fatty acids are carboxylic acids with long hydrocarbon chains. Fatty acids undergo β oxidation when…