Part 1: Determining the absolute configuration of chiral centers in pharmaceuticals. 1. Please assign priorities for the groups on the indicated chiral centers and then rotate the molecule such that the lowest priority group is facing back into the plane of the paper. For help please view the chemical structures of these molecules using the supporting files. A. Assign priorities to the indicated Chiral Center B. HO OH NH₂ linospril (Dapril): Used in the treatment of high blood pressure HO simvastatin (Zocor): used to treat high cholesterol Redraw the molecule with the lowest priority to the back into the plane of the paper. Rotate Lowest Priority to the Back Rotate Lowest Priority to the Back The indicated chiral cente The indicated chiral center is

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Ignore the avogadro part
Part 1: Determining the absolute configuration of chiral centers in pharmaceuticals.
1. Please assign priorities for the groups on the indicated chiral centers and then
rotate the molecule such that the lowest priority group is facing back into the
plane of the paper. For help please view the chemical structures of these
molecules using the supporting files.
A.
Assign priorities to the indicated Chiral Center
B.
HO
O
НО.
-OH
NH₂
linospril (Dapril): Used in the
treatment of high blood pressure
simvastatin (Zocor): used to treat
high cholesterol
Redraw the molecule with the lowest priority to
the back into the plane of the paper.
Rotate Lowest Priority
to the Back
Rotate Lowest Priority
to the Back
The indicated chiral
cente
The indicated chiral
center is
Transcribed Image Text:Part 1: Determining the absolute configuration of chiral centers in pharmaceuticals. 1. Please assign priorities for the groups on the indicated chiral centers and then rotate the molecule such that the lowest priority group is facing back into the plane of the paper. For help please view the chemical structures of these molecules using the supporting files. A. Assign priorities to the indicated Chiral Center B. HO O НО. -OH NH₂ linospril (Dapril): Used in the treatment of high blood pressure simvastatin (Zocor): used to treat high cholesterol Redraw the molecule with the lowest priority to the back into the plane of the paper. Rotate Lowest Priority to the Back Rotate Lowest Priority to the Back The indicated chiral cente The indicated chiral center is
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