Page of 10 ZOOM b) A strong acid is generally used to catalyze the Fischer esterification of carboxylic acids. What two steps in the reaction are accelerated by the presence of strong acid? What function does the acid play in each of these steps? c) Excess carboxylic acid (if any) was removed from the reaction mixture by the addition of Na,CO; solution (a basic solution). What side reaction might occur if you made the solution 6 strongly basic with aqueous sodium hydroxide? Write this reaction. (Hint: What happens to the ester in the presence of NaOH?)
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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