Oxford survey of childhood cancers Begun in 1955, this project encompasses potentially all children in Britain with cancer since 1953. A total of 8,513 cases were enrolled until 1967. For each case, a healthy control is selected from local birth registration lists, matched by age, sex and region of residence. Data concerning each case and control are obtained by interviewing mothers and by available medical records. Prime attention is paid to prenatal events as potential oncogenic factors and, in particular, maternal exposure to diagnostic irradiation during gestation. The table below shows some of the data in the study. 1.  identify if the design is prospective or retrospective.  2. Compute for and interpret the measure of association between the exposure and outcome.

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 Oxford survey of childhood cancers Begun in 1955, this project encompasses potentially all children in Britain with cancer since 1953. A total of 8,513 cases were enrolled until 1967. For each case, a healthy control is selected from local birth registration lists, matched by age, sex and region of residence. Data concerning each case and control are obtained by interviewing mothers and by available medical records. Prime attention is paid to prenatal events as potential oncogenic factors and, in particular, maternal exposure to diagnostic irradiation during gestation. The table below shows some of the data in the study.

1.  identify if the design is prospective or retrospective. 

2. Compute for and interpret the measure of association between the exposure and outcome. 

Table 2. Distribution of participants of the Oxford survey of
childhood cancers, Great Britain, 1955-1967
Cases of
childhood cancer
Maternal X-ray
during pregnancy
Yes
No
TOTAL
1,181
7,332
8,513
Healthy controls
840
7,673
8,513
Transcribed Image Text:Table 2. Distribution of participants of the Oxford survey of childhood cancers, Great Britain, 1955-1967 Cases of childhood cancer Maternal X-ray during pregnancy Yes No TOTAL 1,181 7,332 8,513 Healthy controls 840 7,673 8,513
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