One of the factors that determines the degree of risk a pesticide poses to human health is the rate at which the pesticide is absorbed into skin after contact. An important question is whether the amount in the skin continues to increase with the length of the contact, or whether it increases for only a short time before leveling off. To investigate this, measured amounts of a certain pesticide were applied to  20  samples of rat skin. Four skins were analyzed at each of the time intervals  1 ,   2 ,   4 ,   10 ,  and  24  hours. The amounts of the chemical (in micrograms) that were in the skin are given in the following table.   Duration   Amounts Absorbed 1   1.3 1.4 1.3 2.1 2   1.6 2.0 1.3 2.0 4   1.9 1.6 2.1 1.7 10   2.0 2.1 2.0 1.7 24   2.4 2.2 2.6 2.2 Can you conclude that the amount in the skin varies with time? Use the  =α0.001  level of significance and the ANOVA table shown below. One-way ANOVA: Pesticide Amount Source DF SS MS F P Duration 4 1.5150 0.37875 4.97 0.009 Error 15 1.143 0.07617     Total 19 2.657       Is there enough evidence to conclude that the mean amount of pesticide in the skin varies with time?

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One of the factors that determines the degree of risk a pesticide poses to human health is the rate at which the pesticide is absorbed into skin after contact. An important question is whether the amount in the skin continues to increase with the length of the contact, or whether it increases for only a short time before leveling off. To investigate this, measured amounts of a certain pesticide were applied to 

20

 samples of rat skin. Four skins were analyzed at each of the time intervals 

1

,  

2

,  

4

,  

10

,  and 

24

 hours. The amounts of the chemical (in micrograms) that were in the skin are given in the following table.

 

Duration   Amounts Absorbed
1
 
1.3
1.4
1.3
2.1
2
 
1.6
2.0
1.3
2.0
4
 
1.9
1.6
2.1
1.7
10
 
2.0
2.1
2.0
1.7
24
 
2.4
2.2
2.6
2.2

Can you conclude that the amount in the skin varies with time? Use the 

=α0.001

 level of significance and the ANOVA table shown below.

One-way ANOVA: Pesticide Amount
Source DF SS MS F P
Duration
4
1.5150
0.37875
4.97
0.009
Error
15
1.143
0.07617
   
Total
19
2.657
     

Is there enough evidence to conclude that the mean amount of pesticide in the skin varies with time?

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