Protease enzymes cleave proteins by hydrolyzing peptidebonds. The strategy for each type of metalloprotease beginswith generating a nucleophile that attacks the peptide bondthat attacks the peptide carbonyl group.Macmillan LearningOn the basis of the information provided in the figure, showthe next step in the mechanism for peptide-bond cleavageby a cysteine protease.HCysteine proteasesR₂HNR₁Draw curved arrows on the pre-drawn structures toshow the cysteine protease mechanism. If you need toreset the structures, click More followed byReset Drawing.Select Draw Templates Groups MoreNR2H\..COSR1EraseN Draw curved arrows on the pre-drawn structures toshow the cysteine protease mechanism. If you need toreset the structures, click More followed byReset Drawing.Select Draw Templates Groups More✔Enz+NHR2I..R1EnzEraseQ2 Q२

Proteins that catalyse the hydrolytic cleavage of peptide bonds are called proteases. Cysteine…

Answered: On the basis of the information…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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On the basis of the information provided in the figure, show the next step in the mechanism for peptide-bond cleavage by a cysteine protease. Cysteine proteases