On the basis of the information provided in the figure, show the next step in the mechanism for peptide-bond cleavage by a cysteine protease. Cysteine proteases

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Protease enzymes cleave proteins by hydrolyzing peptide
bonds. The strategy for each type of metalloprotease begins
with generating a nucleophile that attacks the peptide bond
that attacks the peptide carbonyl group.
Macmillan Learning
On the basis of the information provided in the figure, show
the next step in the mechanism for peptide-bond cleavage
by a cysteine protease.
H
Cysteine proteases
R₂
HN
R₁
Draw curved arrows on the pre-drawn structures to
show the cysteine protease mechanism. If you need to
reset the structures, click More followed by
Reset Drawing.
Select Draw Templates Groups More
N
R2
H
\..
C
O
S
R1
Erase
N
Transcribed Image Text:Protease enzymes cleave proteins by hydrolyzing peptide bonds. The strategy for each type of metalloprotease begins with generating a nucleophile that attacks the peptide bond that attacks the peptide carbonyl group. Macmillan Learning On the basis of the information provided in the figure, show the next step in the mechanism for peptide-bond cleavage by a cysteine protease. H Cysteine proteases R₂ HN R₁ Draw curved arrows on the pre-drawn structures to show the cysteine protease mechanism. If you need to reset the structures, click More followed by Reset Drawing. Select Draw Templates Groups More N R2 H \.. C O S R1 Erase N
Draw curved arrows on the pre-drawn structures to
show the cysteine protease mechanism. If you need to
reset the structures, click More followed by
Reset Drawing.
Select Draw Templates Groups More
✔
Enz
+N
H
R2
I..
R1
Enz
Erase
Q2 Q
२
Transcribed Image Text:Draw curved arrows on the pre-drawn structures to show the cysteine protease mechanism. If you need to reset the structures, click More followed by Reset Drawing. Select Draw Templates Groups More ✔ Enz +N H R2 I.. R1 Enz Erase Q2 Q २
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