On the basis of the information provided in the figure, show the next step in the mechanism for peptide-bond cleavage by a cysteine protease. Cysteine proteases
On the basis of the information provided in the figure, show the next step in the mechanism for peptide-bond cleavage by a cysteine protease. Cysteine proteases
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question

Transcribed Image Text:Protease enzymes cleave proteins by hydrolyzing peptide
bonds. The strategy for each type of metalloprotease begins
with generating a nucleophile that attacks the peptide bond
that attacks the peptide carbonyl group.
Macmillan Learning
On the basis of the information provided in the figure, show
the next step in the mechanism for peptide-bond cleavage
by a cysteine protease.
H
Cysteine proteases
R₂
HN
R₁
Draw curved arrows on the pre-drawn structures to
show the cysteine protease mechanism. If you need to
reset the structures, click More followed by
Reset Drawing.
Select Draw Templates Groups More
N
R2
H
\..
C
O
S
R1
Erase
N

Transcribed Image Text:Draw curved arrows on the pre-drawn structures to
show the cysteine protease mechanism. If you need to
reset the structures, click More followed by
Reset Drawing.
Select Draw Templates Groups More
✔
Enz
+N
H
R2
I..
R1
Enz
Erase
Q2 Q
२
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