Of the following, which represents a logical retrosynthesis for target molecule A? to OH MgBr MgBr OH OH _MgBr он MgBr

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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The following two isomeric ketones were among the 68 compounds isolated from the steam-distilled volatile oil of fresh and air-dried marijuana buds (J. Nat. Prod. 19965949–51). Propose a separate synthesis for each of these two compounds using only disubstituted alkenes containing four carbon atoms as starting materials.

Of the following, which represents a logical retrosynthesis for target molecule A?
Lo
он
MgBr
MgBr
OH
OH
MgBr
OH
`MgBr
Transcribed Image Text:Of the following, which represents a logical retrosynthesis for target molecule A? Lo он MgBr MgBr OH OH MgBr OH `MgBr
Devise a synthesis of ketone B, starting with the disubstituted alkene shown:
в
The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary
reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one
correct solution, provide just one answer.
А
B
DMP or PCC
NBS, hv
2) H30* workup
D
E
F
t-BUOK
HBr, ROOR
Na,Cr207, H2SO4, H2O
G
H
Mg
TSCI, py
HBr
Transcribed Image Text:Devise a synthesis of ketone B, starting with the disubstituted alkene shown: в The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. А B DMP or PCC NBS, hv 2) H30* workup D E F t-BUOK HBr, ROOR Na,Cr207, H2SO4, H2O G H Mg TSCI, py HBr
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For step 4 synthesis can you explain what each reagent does in the synthesis? Like, expand on if it's an addition reaction or substitution or elimination and what type, etc. 

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