odd-chain fatty acids are metabolized down. propionyl-CoA (a 3 Carbon unit). This is converted in three steps to succinyl-CoA (as shown below). Calculate the number of ATPs that would result from the complete oxidation of valeric acid (a C-5 fatty acid)

odd-chain fatty acids are metabolized down. propionyl-CoA (a 3 Carbon unit). This is converted in three steps to succinyl-CoA (as shown below). Calculate the number of ATPs that would result from the complete oxidation of valeric acid (a C-5 fatty acid)

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Fatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.
On these following choices, Malonyl CoA synthase, Malonyl CoA synthetase, Acetyl CoA carboxylase and Acetyl CoA decarboxylase, what is the correct answer in fatty acid synthesis?
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Arrange the steps of breakdown of oleic acid (pictured below) in the correct order. 1 2 3 4 5 activation by acyl-CoAsynthe ✓ [Choose ] one cycle ofß-oxidationbeginning at the enoyl-CoAhydratasestep three cycles ofẞ-oxidation five cycles ofß-oxidation activation by acyl-CoAsynthetase enoyl-CoAisomeraseactivity enoyl-CoAisomeraseactivity V one cycle ofß-oxidationbegini V five cycles ofß-oxidation OH
Acetyl-CoA + HCO3- → Malonyl-CoA However, the ΔG of this reaction is much greater than zero. In other words, it is endergonic. Which of the following reactions is most likely to be coupled to the carboxylation of acetyl-CoA so that it can occur? the isomerization of glucose 6-phosphate into fructose 6-phosphate - a readily reversible reaction with a negative ΔG the dehydration of 2-phosphoglycerate into phosphoenolpyruvate - a readily reversible reaction with a positive ΔG the hydrolysis of ATP into ADP and Pi - an essentially irreversible reaction with a negative ΔG the reduction of NAD+ into NADH - an essentially irreversible reaction with a positive ΔG
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Identify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis. Carry your pathway as far as the rate-determining reaction in cholesterol biosynthesis. Drag the appropriate labels to their respective targets. succinyl-CoA succinate acetyl-CoA CoA-SH acetoacetyl-CoA HMG-CoA 2NADP 2NADPH+ 2H acetoacetate K UHL return to a mevalonate + CoA-SH
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