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Ocular albinism is a sex-linked recessive disease carried on the X chromosome. A female carrier mates with a male with this disorder. What percentage of all of their children is predicted to be an albino female? 1) 0% 2) 25% 3) 50% 4) 75% 5) 100%

Ocular albinism is a sex-linked recessive disease carried on the X chromosome. A female carrier mates with a male with this disorder. What percentage of all of their children is predicted to be an albino female? 1) 0% 2) 25% 3) 50% 4) 75% 5) 100%

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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### Understanding Ocular Albinism Inheritance **Question:** Ocular albinism is a sex-linked recessive disease carried on the X chromosome. A female carrier mates with a male with this disorder. What percentage of all of their children is predicted to be an albino female? **Options:** 1. 0% 2. 25% 3. 50% 4. 75% 5. 100% #### Explanation: To solve this question, it is useful to understand how sex-linked recessive traits are inherited. - Ocular albinism is carried on the X chromosome. - Females have two X chromosomes (XX) while males have one X and one Y chromosome (XY). - A female carrier has one normal allele and one allele for ocular albinism (XᵃX). - A male with the disorder has one affected X chromosome and one Y chromosome (XᵃY). ##### Punnett Square Analysis: Let's cross the genotypes of the female carrier (XᵃX) and the affected male (XᵃY). | Xᵃ | X | --|----|---| Xᵃ|XᵃXᵃ|XᵃX| Y |XᵃY |XY | - XᵃXᵃ : Female with the disorder. - XᵃX : Female carrier. - XᵃY : Male with the disorder. - XY : Unaffected male. From the Punnett Square, we can see: - There is a 25% chance of getting an albino female (XᵃXᵃ). - There is a 25% chance of getting a female carrier (XᵃX). - There is a 25% chance of getting an affected male (XᵃY). - There is a 25% chance of getting an unaffected male (XY). #### Conclusion: The percentage of all children predicted to be an albino female is **25%**. **Correct Answer:** 2) 25%
Transcribed Image Text:### Understanding Ocular Albinism Inheritance **Question:** Ocular albinism is a sex-linked recessive disease carried on the X chromosome. A female carrier mates with a male with this disorder. What percentage of all of their children is predicted to be an albino female? **Options:** 1. 0% 2. 25% 3. 50% 4. 75% 5. 100% #### Explanation: To solve this question, it is useful to understand how sex-linked recessive traits are inherited. - Ocular albinism is carried on the X chromosome. - Females have two X chromosomes (XX) while males have one X and one Y chromosome (XY). - A female carrier has one normal allele and one allele for ocular albinism (XᵃX). - A male with the disorder has one affected X chromosome and one Y chromosome (XᵃY). ##### Punnett Square Analysis: Let's cross the genotypes of the female carrier (XᵃX) and the affected male (XᵃY). | Xᵃ | X | --|----|---| Xᵃ|XᵃXᵃ|XᵃX| Y |XᵃY |XY | - XᵃXᵃ : Female with the disorder. - XᵃX : Female carrier. - XᵃY : Male with the disorder. - XY : Unaffected male. From the Punnett Square, we can see: - There is a 25% chance of getting an albino female (XᵃXᵃ). - There is a 25% chance of getting a female carrier (XᵃX). - There is a 25% chance of getting an affected male (XᵃY). - There is a 25% chance of getting an unaffected male (XY). #### Conclusion: The percentage of all children predicted to be an albino female is **25%**. **Correct Answer:** 2) 25%
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