Now that you have learned what an esterification reaction is let me ask you a question. Which of the following molecules do you think would be the correct reagents to perform such a reaction? CH₂ Diethyl ether A 1. B and D 2. A and B 3. A and C 4. Cand D CH₂ OH Benzoic acid B H₂C. Ethyl propionate C

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Synthesis of Aspirin: How to fight students'
migraines
Question 1:
Now that you have learned what an esterification reaction is let me ask you a question. Which of the following molecules do
you think would be the correct reagents to perform such a reaction?
CH₂
Diethyl ether
A
CH3
OH
Benzoic acid
B
1. B and D
2. A and B
3. A and C
4. Cand D
Question 2: Now that we are here, which step would you take next in your synthetic route?
1. Clip the flask to the support above the water bath to secure it
2. Insert the condenser in the flask to start the reflux
3. Connect the water tubes to the condenser and run the warm water
4. Place the flask on the table and insert the condenser
H₂C
Ethyl propionate
C
Question 3: But now we do have our crystals, so let's focus on the yield. Why do you think it is important to wait until the
crystals are dry before calculating the yield?
1. Because otherwise the mass of water will add weight on the scale
2. Because water will react with the product
3. Because water will form hydrogen bonds with the product
4. Because the molecular mass of water will influence the yield
Question 4: One final question. What is the main information you wish to acquire when performing a melting point analysis?
1. Whether the conversion from reagent to product was successful
2. The percentage of impurities in your sample
3. How much reagent has successfully turned into product
4. The average size of crystals after the crystallization process
Question 5:
Now you know everything about our crystals. Let me ask you, which temperature would you assign the meniscus point to?
Have a look at the image if you're in doubt about what the meniscus point is.
Transcribed Image Text:Synthesis of Aspirin: How to fight students' migraines Question 1: Now that you have learned what an esterification reaction is let me ask you a question. Which of the following molecules do you think would be the correct reagents to perform such a reaction? CH₂ Diethyl ether A CH3 OH Benzoic acid B 1. B and D 2. A and B 3. A and C 4. Cand D Question 2: Now that we are here, which step would you take next in your synthetic route? 1. Clip the flask to the support above the water bath to secure it 2. Insert the condenser in the flask to start the reflux 3. Connect the water tubes to the condenser and run the warm water 4. Place the flask on the table and insert the condenser H₂C Ethyl propionate C Question 3: But now we do have our crystals, so let's focus on the yield. Why do you think it is important to wait until the crystals are dry before calculating the yield? 1. Because otherwise the mass of water will add weight on the scale 2. Because water will react with the product 3. Because water will form hydrogen bonds with the product 4. Because the molecular mass of water will influence the yield Question 4: One final question. What is the main information you wish to acquire when performing a melting point analysis? 1. Whether the conversion from reagent to product was successful 2. The percentage of impurities in your sample 3. How much reagent has successfully turned into product 4. The average size of crystals after the crystallization process Question 5: Now you know everything about our crystals. Let me ask you, which temperature would you assign the meniscus point to? Have a look at the image if you're in doubt about what the meniscus point is.
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