No disjunction is the reason we get chromosome number anomalies. Explain?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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No disjunction is the reason we get chromosome number anomalies. Explain?

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Chromosomes are present in the nucleus of the cell and are actually a compilation of the cell’s DNA. DNA carries the genetic information and helps to maintain heridity. In human there are 23 pairs of chromosomes present. In few rare cases some anomalies occurs that may cause change in the number of the chromosomes or change the ploidy level of the cell among them one is Non disjunction. This is mainly caused when the sister chromatids are unable to separate during the anaphase of cell division leading to one cell having more number of chromosome and the other cell having less chromosome number.

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