NH Amidines have the general form R nitrogen analogs of carboxylic acids. As shown here, they can be hydrolyzed under basic conditions to form amides. Propose a mechanism showing the conversion of an amidine to an amide. NH2, so they are NH HO 1 `NH, H2O R `NH2

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Chapter1: Chemical Foundations
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NH
Amidines have the general form R
nitrogen analogs of carboxylic acids. As shown here, they
can be hydrolyzed under basic conditions to form amides.
Propose a mechanism showing the conversion of an
amidine to an amide.
NH2, so they are
NH
HO 1
`NH, H2O
R
`NH2
Transcribed Image Text:NH Amidines have the general form R nitrogen analogs of carboxylic acids. As shown here, they can be hydrolyzed under basic conditions to form amides. Propose a mechanism showing the conversion of an amidine to an amide. NH2, so they are NH HO 1 `NH, H2O R `NH2
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