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Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Need a b
9. A cell membrane at 37°C is found to be permeable to Ca²+ but not to anions, and analysis shows the inside concentration to be 0.200 M and the outside concentration to be 0.005 M in Ca?+. a) What potential difference in volts would have to exist across the membrane for Ca?+ to be in equilibrium at the stated concentrations? Assume that activity coefficients are equal to 1. Give the sign of the potential inside with respect to that outside. b) If the measured inside potential is +100 mV with respect to the outside, what is the minimum (reversible) work required to transfer 1 mol of Ca²+ from outside to inside under these conditions?
Transcribed Image Text:9. A cell membrane at 37°C is found to be permeable to Ca²+ but not to anions, and analysis shows the inside concentration to be 0.200 M and the outside concentration to be 0.005 M in Ca?+. a) What potential difference in volts would have to exist across the membrane for Ca?+ to be in equilibrium at the stated concentrations? Assume that activity coefficients are equal to 1. Give the sign of the potential inside with respect to that outside. b) If the measured inside potential is +100 mV with respect to the outside, what is the minimum (reversible) work required to transfer 1 mol of Ca²+ from outside to inside under these conditions?
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