Chemistry In Focus
6th Edition
ISBN:9781305084476
Author:Tro, Nivaldo J., Neu, Don.
Publisher:Tro, Nivaldo J., Neu, Don.
Chapter18: The Chemistry Of Food
Section: Chapter Questions
Problem 37E
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Concept explainers
Organomagnesium compounds
The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.
Hydrolysis Grignard Reactions and Reduction
Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.
Question
Devise a synthesis of anastrozole, a drug used to reduce the recurrence of breast cancer (Section 22.18), from the given compounds. You may use any other needed organic compounds or inorganic reagents.
![NC.
Br.
Br
HN-
.CN
anastrozole](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe013460a-845f-4c1f-b90f-4cf4ecf889b2%2F7f3fe85b-2252-48ba-a715-e353f5a5af77%2Fyqkxs9l.png&w=3840&q=75)
Transcribed Image Text:NC.
Br.
Br
HN-
.CN
anastrozole
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