Name: Mary Ethnicity: Caucasian female Height: 69" Age: 50 Weight: 130 lbs. Mary is a 50 year old female presents with nocturnal paroxysmal dyspnea, orthopnea, palpitations, and fatigue. An electrocardiogram demonstrates a thickened, immobile mitral valve with anterior and posterior leaflets moving together, slow early diastolic filling of the ventricles and left atrial enlargement. Investigational Framework What is the probable cause of the women's symptoms? Explain the pathological significance of slow early diastolic filling of the ventricles, palpations and left atrial enlargement? Given the echocardiograph, what type of murmur would you expect to find? Would the pulmonary or systemic circulation be affected as the women's mitral value disorder progresses?

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