Mutation rate is higher at synonymous sites than at nonsynonymous sites Synonymous sites 3.0 2.0 1.0 Nonsynonymous sites 1 3 Divergence time (x 10º) FIGURE 20-8 The amount of ure of purifying selec- how that synonymous ; they show that these nutations that change o effect on the amino nucleotide divergence at synonymous sites is greater than the amount of divergence at nonsynonymous sites of the B-globin gene. Number of substitutions per nucleotide

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Examining Figure 20-8, explain why the rate of evolution
at nonsynonymous sites is lower. Do you expect this to be
true only of globin genes or of most genes?

Mutation rate is higher at synonymous
sites than at nonsynonymous sites
Synonymous
sites
3.0
2.0
1.0
Nonsynonymous
sites
1
3
Divergence time (x 10º)
FIGURE 20-8 The amount of
ure of purifying selec-
how that synonymous
; they show that these
nutations that change
o effect on the amino
nucleotide divergence at synonymous
sites is greater than the amount of
divergence at nonsynonymous sites of
the B-globin gene.
Number of substitutions per nucleotide
Transcribed Image Text:Mutation rate is higher at synonymous sites than at nonsynonymous sites Synonymous sites 3.0 2.0 1.0 Nonsynonymous sites 1 3 Divergence time (x 10º) FIGURE 20-8 The amount of ure of purifying selec- how that synonymous ; they show that these nutations that change o effect on the amino nucleotide divergence at synonymous sites is greater than the amount of divergence at nonsynonymous sites of the B-globin gene. Number of substitutions per nucleotide
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