Homework Help is Here – Start Your Trial Now!
Science
Anatomy and Physiology
Mismatch repair corrects replicative errors 3 -GÁTC CTAG 3' GATC 5 - CTAG- Muts recognizes mismatched pair. Muts 3' -GÁTC- CTAG 3 GATC -CTAG 5' 3' MutH recognizes methylated parent strand and nicks daughter strand. Mutl MutH 5 3 GÁTC CTAG 3' GATC CTAG 5' 3' New strand is excised and replaced between nick and mismatched pair. 3 GÁTC. СТАG 3' GATÇ - CTAG 5' G .C FIGURE 16-23 Model for mismatch repair in E. col. DNA is methylated (Me) at the A residue in the sequence GATC. DNA repication yields a hemimethylated duplex that exists until methylase can modify the newly synthesized strand. The mismatch- repair system makes any necessary corrections based on the sequence found on the methylated strand (original template). MutS, MutH, and Mut. are proteins. d between the n human mis- nly the newly exing in organ- and C. elegans. gnition of free strands. peat sequences in n io

Mismatch repair corrects replicative errors 3 -GÁTC CTAG 3' GATC 5 - CTAG- Muts recognizes mismatched pair. Muts 3' -GÁTC- CTAG 3 GATC -CTAG 5' 3' MutH recognizes methylated parent strand and nicks daughter strand. Mutl MutH 5 3 GÁTC CTAG 3' GATC CTAG 5' 3' New strand is excised and replaced between nick and mismatched pair. 3 GÁTC. СТАG 3' GATÇ - CTAG 5' G .C FIGURE 16-23 Model for mismatch repair in E. col. DNA is methylated (Me) at the A residue in the sequence GATC. DNA repication yields a hemimethylated duplex that exists until methylase can modify the newly synthesized strand. The mismatch- repair system makes any necessary corrections based on the sequence found on the methylated strand (original template). MutS, MutH, and Mut. are proteins. d between the n human mis- nly the newly exing in organ- and C. elegans. gnition of free strands. peat sequences in n io

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

The MutH protein nicks the newly synthesized strand
(Figure 16-23). How does it “know” which strand this is?

Mismatch repair corrects replicative errors 3 -GÁTC CTAG 3' GATC 5 - CTAG- Muts recognizes mismatched pair. Muts 3' -GÁTC- CTAG 3 GATC -CTAG 5' 3' MutH recognizes methylated parent strand and nicks daughter strand. Mutl MutH 5 3 GÁTC CTAG 3' GATC CTAG 5' 3' New strand is excised and replaced between nick and mismatched pair. 3 GÁTC. СТАG 3' GATÇ - CTAG 5' G .C FIGURE 16-23 Model for mismatch repair in E. col. DNA is methylated (Me) at the A residue in the sequence GATC. DNA repication yields a hemimethylated duplex that exists until methylase can modify the newly synthesized strand. The mismatch- repair system makes any necessary corrections based on the sequence found on the methylated strand (original template). MutS, MutH, and Mut. are proteins. d between the n human mis- nly the newly exing in organ- and C. elegans. gnition of free strands. peat sequences in n io
Transcribed Image Text:Mismatch repair corrects replicative errors 3 -GÁTC CTAG 3' GATC 5 - CTAG- Muts recognizes mismatched pair. Muts 3' -GÁTC- CTAG 3 GATC -CTAG 5' 3' MutH recognizes methylated parent strand and nicks daughter strand. Mutl MutH 5 3 GÁTC CTAG 3' GATC CTAG 5' 3' New strand is excised and replaced between nick and mismatched pair. 3 GÁTC. СТАG 3' GATÇ - CTAG 5' G .C FIGURE 16-23 Model for mismatch repair in E. col. DNA is methylated (Me) at the A residue in the sequence GATC. DNA repication yields a hemimethylated duplex that exists until methylase can modify the newly synthesized strand. The mismatch- repair system makes any necessary corrections based on the sequence found on the methylated strand (original template). MutS, MutH, and Mut. are proteins. d between the n human mis- nly the newly exing in organ- and C. elegans. gnition of free strands. peat sequences in n io
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Anatomy and Physiology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Anatomy & Physiology
Anatomy & Physiology
Anatomy and Physiology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy
Human Anatomy
Anatomy and Physiology
ISBN:
9780135168059
Author:
Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher:
Pearson Education, Inc.,
Anatomy & Physiology: An Integrative Approach
Anatomy & Physiology: An Integrative Approach
Anatomy and Physiology
ISBN:
9780078024283
Author:
Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher:
McGraw-Hill Education
Human Anatomy & Physiology (Marieb, Human Anatomy…
Human Anatomy & Physiology (Marieb, Human Anatomy…
Anatomy and Physiology
ISBN:
9780321927040
Author:
Elaine N. Marieb, Katja Hoehn
Publisher:
PEARSON
SEE MORE TEXTBOOKS