Messner and Habeler's 1978 ascent of Mount Everest without oxygen-breathing apparatus is often described as one of the most remarkable physical accomplishments achieved by humans. Table 1 shows respiratory gas and arterial pH values measured in a resting mountaineer at sea level, Everest base camp and Everest summit. Use the differences in these values to explain how breathing regulation changes when at rest at the 3 altitudes indicated. Calculations are not required but you may wish to consider the role of central and peripheral chemoreceptors and their relationship to paCO,, minute ventilation and alveolar po, in your response. Table 1: Respiratory gas composition and arterial pH measured in a resting mountaineer at sea-level, Everest base-camp and Everest summit. Sea Level Everest Base Camp Everest Summit Altitude (m) 0 5,400 8,848 Barometric Pressure mmHg 760 404 252 Inspired Alveolar p02 (FIO₂) pO2 (PAO₂) mmHg mmHg 150 75 43 106 51 34 Arterial PCO₂ (paCO2) mmHg 36 20.4 7.5 Arterial pH 7.4 7.6 7.9

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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1.Use the differences in these values to explain how breathing regulation changes when at rest at the 3 altitudes indicated. Calculations are not required but you may wish to consider the role of central and peripheral chemoreceptors and their relationship to paCO,, minute ventilation and alveolar pO, in your response.
Messner and Habeler's 1978 ascent of Mount Everest without oxygen-breathing apparatus is often
described as one of the most remarkable physical accomplishments achieved by humans. Table 1
shows respiratory gas and arterial pH values measured in a resting mountaineer at sea level, Everest
base camp and Everest summit.
Use the differences in these values to explain how breathing
regulation changes when at rest at the 3 altitudes indicated. Calculations are not required but you
may wish to consider the role of central and peripheral chemoreceptors and their relationship to
paCO,, minute ventilation and alveolar pO, in your response.
Table 1: Respiratory gas composition and arterial pH measured in a resting mountaineer at sea-level,
Everest base-camp and Everest summit.
Arterial
Barometric
Alveolar
Inspíred
p02 (FIO2) pO2 (PAO2)
pCO2
(расо2)
Altitude
Pressure
Arterial
(m)
pH
mmHg
mmHg
mmHg
mmHg
Sea Level
760
150
106
36
7.4
Everest
Base
5,400
404
75
51
20.4
7.6
Camp
Everest
8,848
252
43
34
7.5
7.9
Summit
Transcribed Image Text:Messner and Habeler's 1978 ascent of Mount Everest without oxygen-breathing apparatus is often described as one of the most remarkable physical accomplishments achieved by humans. Table 1 shows respiratory gas and arterial pH values measured in a resting mountaineer at sea level, Everest base camp and Everest summit. Use the differences in these values to explain how breathing regulation changes when at rest at the 3 altitudes indicated. Calculations are not required but you may wish to consider the role of central and peripheral chemoreceptors and their relationship to paCO,, minute ventilation and alveolar pO, in your response. Table 1: Respiratory gas composition and arterial pH measured in a resting mountaineer at sea-level, Everest base-camp and Everest summit. Arterial Barometric Alveolar Inspíred p02 (FIO2) pO2 (PAO2) pCO2 (расо2) Altitude Pressure Arterial (m) pH mmHg mmHg mmHg mmHg Sea Level 760 150 106 36 7.4 Everest Base 5,400 404 75 51 20.4 7.6 Camp Everest 8,848 252 43 34 7.5 7.9 Summit
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