Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? (Look at the first arrow coming from the Nitrogen with a lone pair). a. rearrangement c. nucleophilic attack
Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? (Look at the first arrow coming from the Nitrogen with a lone pair). a. rearrangement c. nucleophilic attack
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? (Look at the first arrow coming from the Nitrogen with a lone pair).
a. rearrangement
c. nucleophilic attack
c. nucleophilic attack

Transcribed Image Text:HO
Cod-For
HO
NH₂
melphalan
-N:-
NH₂
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