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Martin, a 25-year-old male, has recently been diagnosed with a mitochondrial disease and is seeking information. You know that mitochondrial disease is a genetic disease caused by a mutation in one of the 22 autosomal chromosomes leading to a reduced function of the mitochondria. Question 11. Martin asks if his exhaustion is associated with his disease - knowing the function of the mitochondria, what would you say to Martin (in lay terms)?$2 Question 12. Martin is concerned about his future children inheriting the disease. Answer the following questions regarding inheritance patterns (you might like to use punnet squares to help you prepare your response, but they don't need to be included in your answer).

Martin, a 25-year-old male, has recently been diagnosed with a mitochondrial disease and is seeking information. You know that mitochondrial disease is a genetic disease caused by a mutation in one of the 22 autosomal chromosomes leading to a reduced function of the mitochondria. Question 11. Martin asks if his exhaustion is associated with his disease - knowing the function of the mitochondria, what would you say to Martin (in lay terms)?$2 Question 12. Martin is concerned about his future children inheriting the disease. Answer the following questions regarding inheritance patterns (you might like to use punnet squares to help you prepare your response, but they don't need to be included in your answer).

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Scenario 5 Martin, a 25-year-old male, has recently been diagnosed with a mitochondrial disease and is seeking information. You know that mitochondrial disease is a genetic disease caused by a mutation in one of the 22 autosomal chromosomes leading to a reduced function of the mitochondria. Question 11. Martin asks if his exhaustion is associated with his disease - knowing the function of the mitochondria, what would you say to Martin (in lay terms)? Question 12. Martin is concerned about his future children inheriting the disease. Answer the following questions regarding inheritance patterns (you might like to use punnet squares to help you prepare your response, but they don't need to be included in your answer). a. If both parents are carriers (heterozygous) for a recessively inherited gene, what percentage of offspring will manifest the disease? b. If only one parent contains a single copy (heterozygous) of a dominantly inherited disorder and the other parent is homozygous recessive, what percentage of offspring will have the disorder? c. A mother is a carrier for an X-linked disease, what percentage of males will manifest the disease? And what percentage of females will manifest the disease? d. Explain why there is a difference in X-linked inheritance patterns.
Transcribed Image Text:Scenario 5 Martin, a 25-year-old male, has recently been diagnosed with a mitochondrial disease and is seeking information. You know that mitochondrial disease is a genetic disease caused by a mutation in one of the 22 autosomal chromosomes leading to a reduced function of the mitochondria. Question 11. Martin asks if his exhaustion is associated with his disease - knowing the function of the mitochondria, what would you say to Martin (in lay terms)? Question 12. Martin is concerned about his future children inheriting the disease. Answer the following questions regarding inheritance patterns (you might like to use punnet squares to help you prepare your response, but they don't need to be included in your answer). a. If both parents are carriers (heterozygous) for a recessively inherited gene, what percentage of offspring will manifest the disease? b. If only one parent contains a single copy (heterozygous) of a dominantly inherited disorder and the other parent is homozygous recessive, what percentage of offspring will have the disorder? c. A mother is a carrier for an X-linked disease, what percentage of males will manifest the disease? And what percentage of females will manifest the disease? d. Explain why there is a difference in X-linked inheritance patterns.
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