Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD 50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD 50 value for FD&C Red Dye No. 40 is >10,000 mg/kg in rats. Assume that the LD 50 value for humans is the same as for rats. Calculate the number of number of glasses of Allura Red sports drink, each containing 11.1 mg of Allura Red, required to reach the LD 50 of 10,000 mg of Allura Red/kg body weight. Assume the person has a body weight of 200 lbs. 2.205 lbs = 1 kg You may assume two significant figures but do not use scientific notation. Do not include units with your answer.
Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD 50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD 50 value for FD&C Red Dye No. 40 is >10,000 mg/kg in rats. Assume that the LD 50 value for humans is the same as for rats.
Calculate the number of number of glasses of Allura Red sports drink, each containing 11.1 mg of Allura Red, required to reach the LD 50 of 10,000 mg of Allura Red/kg body weight. Assume the person has a body weight of 200 lbs.
2.205 lbs = 1 kg
You may assume two significant figures but do not use scientific notation.
Do not include units with your answer.
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