List and describe at least two potential consequences to human health due to the paternal-age effect.
The statistical correlation between the father's age at conception and the biological consequences on the kid is known as the paternal age effect. Birthweight, congenital conditions, lifespan, and psychological repercussions are a few examples of such effects. While higher father age is linked to serious health impacts, a 2017 analysis indicated that the overall rise in issues brought on by paternal age is modest. Despite the fact that paternal age has risen during 1960–1970, this is not thought to pose a serious threat to public health.
The population geneticist James F. Crow stated that the "biggest mutational health hazard to the human genome is fertile older males" since the genetic quality, volume, and motility of sperm may all diminish with age. German physician Wilhelm Weinberg first made an oblique suggestion of the paternal age effect in 1912, and British psychiatrist Lionel Penrose made an explicit one in 1955. More recently, in 1998, in the context of paternity testing, DNA-based research was first conducted.
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