Answered: Liposomes can be made by vigorously…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Liposomes can be made by vigorously mixing phospholipids
(like phosphatidylcholine) in water. When the mixture is
allowed to settle, spherical vesicles form that are surrounded
by a phospholipid bilayer “membrane.” Pharmaceutical
chemists are trying to develop liposomes as a targeted drug
delivery system. By adding the drug of choice to the mixture
described above, liposomes form around the solution of the
drug. Specific proteins can be incorporated into the mixture
that will end up within the phospholipid bilayers of the
liposomes. These proteins are able to bind to targets on the
surface of particular kinds of cells in the body. Explain why
injection of liposome encapsulated pharmaceuticals might
be a good drug delivery system.

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