Lipogenesis, or fatty acid synthesis, occurs in several cycles. A diagram of the reactions of the first cycle of fatty acid synthesis is shown. Select all of the true statements. Malonyl-CoA adds a two-carbon group to the growing fatty acid chain with each cycle. Acetyl-SCOA provides the carbon used for fatty acid synthesis. The reactions of lipogenesis include, but are not limited to, condensation, reduction, and dehydration. The first cycle of lipogenesis yields CO₂, one NADP+, and an acyl group attached to ACP. In lipogenesis, acetyl and acyl molecules are activated by an acyl carrier protein (ACP). Each cycle lengthens the fatty acid chain by three carbon atoms. _i CH3-C-S-KS+ 0-C-CH₂-C-SACP acetyl-ACP malonyl-ACP CO₂ || CH3 C-CH₂-C-SACP NADPH + H+ NADP+ OH || CH3 CH-CH₂-C-SACP H₂O || CH3CH=CH-C-SACP NADPH + H+ NADP+ CH3CH₂CH2-C-SACP

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Lipogenesis, or fatty acid synthesis, occurs in several cycles.
A diagram of the reactions of the first cycle of fatty acid
synthesis is shown.
Select all of the true statements.
Malonyl-CoA adds a two-carbon group to the
growing fatty acid chain with each cycle.
Acetyl-SCOA provides the carbon used for fatty
acid synthesis.
The reactions of lipogenesis include, but are not
limited to, condensation, reduction, and dehydration.
The first cycle of lipogenesis yields CO₂, one
NADP+, and an acyl group attached to ACP.
In lipogenesis, acetyl and acyl molecules are
activated by an acyl carrier protein (ACP).
Each cycle lengthens the fatty acid chain by three
carbon atoms.
_i
CH3-C-S-KS+ 0-C-CH₂-C-SACP
acetyl-ACP
malonyl-ACP
CO2
||
CH3 C-CH₂-C-SACP
NADPH + H+
NADP+
OH
||
CH3 CH-CH₂-C-SACP
H₂O
||
CH3CH=CH-C-SACP
NADPH + H+
NADP+
CH3CH₂CH2-C-SACP
Transcribed Image Text:Lipogenesis, or fatty acid synthesis, occurs in several cycles. A diagram of the reactions of the first cycle of fatty acid synthesis is shown. Select all of the true statements. Malonyl-CoA adds a two-carbon group to the growing fatty acid chain with each cycle. Acetyl-SCOA provides the carbon used for fatty acid synthesis. The reactions of lipogenesis include, but are not limited to, condensation, reduction, and dehydration. The first cycle of lipogenesis yields CO₂, one NADP+, and an acyl group attached to ACP. In lipogenesis, acetyl and acyl molecules are activated by an acyl carrier protein (ACP). Each cycle lengthens the fatty acid chain by three carbon atoms. _i CH3-C-S-KS+ 0-C-CH₂-C-SACP acetyl-ACP malonyl-ACP CO2 || CH3 C-CH₂-C-SACP NADPH + H+ NADP+ OH || CH3 CH-CH₂-C-SACP H₂O || CH3CH=CH-C-SACP NADPH + H+ NADP+ CH3CH₂CH2-C-SACP
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